biology facts

WTF Fun Fact 13715 – Types of RNA

You’ve probably heard of RNA recently because of the new type of RNA vaccines that have saved millions of lives around the world from COVID-19.

But RNA, or ribonucleic acid, is more than just a single entity. It’s actually a family of crucial molecules that vary in form and function, each playing a unique role in how our bodies operate.

Understanding them can help us better understand how our bodies work and why RNA plays such a unique role in everything from viral vaccines to cancer treatments.

The Various Types of RNA and Their Functions

1. Messenger RNA (mRNA)

Imagine mRNA as the diligent courier within a cell. Its primary function is to relay genetic blueprints from DNA to the cell’s protein-manufacturing sites. This RNA type dictates the specific proteins to be synthesized. These proteins are crucial for repair and growth processes within the body. The innovation of mRNA vaccines leverages this property to instruct cells to produce elements that trigger immune responses.

2. Ribosomal RNA (rRNA)

rRNA serves as the core structural and enzymatic component of ribosomes, which are the cellular factories assembling proteins. By interacting with mRNA and various proteins, rRNA helps form the complex structures of ribosomes, ensuring that protein synthesis is precise and efficient. The accuracy of rRNA’s function is vital for the correct folding and function of proteins.

3. Transfer RNA (tRNA)

tRNA functions as the key supplier at the protein synthesis construction site. It carefully selects amino acids and transports them to the ribosome. Then, it matches them to the appropriate codons on the mRNA sequence. This process is crucial for building proteins accurately and efficiently. That’s because each tRNA molecule is specialized for a specific amino acid.

4. MicroRNA (miRNA)

miRNA acts as a critical regulator of gene expression. These short RNA molecules can bind to specific mRNA molecules, blocking their translation into proteins or targeting them for degradation. Through this regulatory function, miRNAs maintain cellular health by ensuring that proteins are synthesized only when needed. This prevents any overproduction that might lead to potential cellular damage.

5. Small Interfering RNA (siRNA)

Similar to miRNA, siRNA regulates gene expression and plays a role in the immune response against pathogens, particularly in plants. By degrading foreign RNA molecules, such as those from viruses, siRNA prevents the replication of the pathogen. This, in turn, helps protect an organism from disease.

The Importance of Understanding

The diversity in RNA types highlights the molecule’s critical roles in cellular function and overall organismal health. By studying these various forms, scientists can develop better therapeutic strategies for plants and humans. So, it can be used for things from enhancing crop resilience to treating genetic disorders and fighting viruses. It offers multiple angles from which medical science can approach the treatment and understanding of diseases.

Understanding RNA’s functions also empowers innovation in medical technology, as seen with mRNA vaccines. Such advancements underscore the potential of this research to yield transformative tools for medicine, providing hope for treatments that are more effective and precisely targeted.

As research continues to unravel the complexities of RNA, its profound impact on both basic biology and applied medical science becomes increasingly clear. This exploration is not just about scientific curiosity but about paving the way for future innovations that could revolutionize healthcare and treatment methodologies worldwide. By appreciating the versatile roles of RNA, we gain deeper insights into the mechanics of life and the potential for significant medical breakthroughs.

— WTF fun facts

Source: “4 Types of RNA” — ThoughtCo

WTF Fun Fact 13544 – What Darwin Ate

You might assume that Charles Darwin, the famed naturalist, was a vegetarian since he was so enamored with living creatures, but he was just the opposite – in fact, Darwin ate some of his discoveries.

During his journey on The Beagle, he indulged in an array of exotic meats – from puma, which he found “remarkably like veal in taste,” to armadillos and iguanas.

His curiosity even led him to taste the bladder contents of a giant tortoise. Darwin’s palate wasn’t just adventurous; it was scientific. He was known for eating specimens he was studying and trying to describe scientifically.

Modern Biologists Follow Suit

This gastronomic curiosity didn’t end with Darwin. Many modern scientists continue to eat their study subjects, either out of convenience (as with those researching edible plants and animals like trout or blueberries) or driven by sheer curiosity. From bluegill and sea urchin to more peculiar choices like beetles and cicadas, the range of their dietary experiments is vast.

Notably, Richard Wassersug, while conducting a study on the palatability of tadpoles in the 1970s, had graduate students (bribed with beer) taste but not swallow various tadpole species. This experiment, now impossible to conduct due to ethical restrictions, showed that easy-to-catch tadpoles often tasted worse. Wassersug himself described the taste of toad tadpoles as “astonishingly bitter.”

The Drive Behind Why Darwin Ate an Unusual Diet

The motivation behind these gastronomic explorations varies. Sometimes it’s an academic pursuit, as in Wassersug’s study. Other times, it’s a quest to manage invasive species, turning them from pests into menu items. Sarah Treanor Bois, during her Ph.D. research on invasive plants, attended a cook-off featuring dishes made from invasive species like nutria and bullfrog legs. Eating invasives is not just about satiating curiosity but also about drawing attention to ecological problems.

However, the most common reason cited for these unusual diets is pure scientific curiosity. Robert Thorson, a geologist, once tasted 30,000-year-old meat from a giant steppe bison found in permafrost. His verdict? It was stringy and flavorless, with a “pungent rankness.”

Scientists’ Gastronomic Adventures

Why are scientists so inclined towards tasting their research subjects? Mark Siddall, a leech expert, believes it’s about familiarity. Just as an omnivore eats chicken, beef, or pork, scientists consume what they’re familiar with. To a biologist, an organism they’ve studied extensively may not seem so different from regular food. Richard Wassersug views it as a part of being a naturalist. To fully understand and connect with nature, one must engage all senses, including taste.

It’s not just about curiosity but also about a sense of community and perhaps a bit of competitiveness among scientists. The stories of Darwin and others set a precedent, and many modern scientists feel compelled to follow in their footsteps, driven by peer or ‘beer’ pressure.

— WTF fun facts

Source: “Dining Like Darwin: When Scientists Swallow Their Subjects” — NPR