WTF Fun Fact 13749 – Worm Therapy

What would make you agree to worm therapy? When you hear what they can do, you might be more interested than you could have imagined.

Imagine curing severe allergies or autoimmune diseases not with advanced biotech drugs but with worms? Yes, the creepy crawlies might just be the unexpected heroes in the saga of human health, specifically gut-dwelling parasites like hookworms.

Hookworms: The Gut’s Unlikely Allies

In a twist that might make even the bravest squirm, recent research explores using parasitic worms as a potential treatment for autoimmune diseases. This idea stems from an intriguing theory: these parasites, by damping down our immune systems, might stop it from attacking our own bodies—an overreaction that’s a hallmark of autoimmune issues.

Science writer Moises Velasquez-Manoff, inspired by personal health challenges including alopecia and hay fever, ventured into this uncharted territory. His journey led him to Tijuana, where he intentionally infected himself with 30 hookworms. Yes, you read that right—Velasquez-Manoff allowed nearly three dozen parasites to take up residence in his intestines.

A Microscopic Invasion with Macro Implications

Hookworm larvae start their invasion by burrowing into the skin. They journey through the bloodstream to the lungs, then migrate to the small intestine where they clamp onto the intestinal walls and start feeding on the host’s blood. While this sounds like something out of a horror film, the real shocker comes from what happens next.

Once settled in the gut, these worms perform a bit of immunological magic. They suppress the immune system just enough to avoid being attacked by it. Researchers like P’ng Loke from the New York University School of Medicine suggest that this could prevent the immune system from overreacting. In theory, this should help alleviate symptoms of autoimmune diseases.

The Clinical Trial Turbulence

Excited by the potential, a pharmaceutical company, Coronado Biosciences, launched clinical trials to test this theory. They explored whether pig whipworms could help patients with Crohn’s disease. However, the results were disappointing. The trials showed that the patients who received the worm treatment did no better than those who took a placebo. Consequently, Coronado Biosciences saw its stock value crash and eventually shifted its business focus after canceling further trials.

Despite the setbacks in clinical trials, the concept of using parasitic worms for treating autoimmune diseases isn’t dead. The mixed results hint at a complex relationship between humans and parasites, possibly influenced by genetic factors or the specific conditions of the trials.

Velasquez-Manoff’s Personal Experiment

Back to our adventurous science writer—Velasquez-Manoff noticed significant temporary relief from his hay fever post-infestation. He even saw signs of hair growth, although minor. Unfortunately, the positive effects didn’t last. His symptoms returned, and the side effects of hosting the worms—like diarrhea and cramps—made the whole ordeal quite unpleasant.

Worm Therapy: A Gutsy Move?

Velasquez-Manoff’s personal conclusion was clear: the discomfort and risks of worm therapy did not outweigh its transient benefits. His experience underscores the complexity of biohacking with parasites. What works as a theoretical treatment might not translate into a practical or comfortable solution.

The Future of Worm Therapy

The journey of using parasites as a treatment is still in its infancy. While some may hold onto hope for worm-based therapies, current evidence suggests a cautious approach. Future research needs to address the variability in treatment outcomes and the potential long-term effects of such therapies.

In the meantime, those suffering from allergies or autoimmune diseases might want to stick to more conventional treatments. And as for the rest of us, perhaps it’s best to keep the worms in the garden, and out of our guts, at least for now.

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Source: “Could Worms In Your Gut Cure Your Allergies?” — NPR

WTF Fun Fact 13748 – The Klondike Big Inch Land Co.

Have you heard of the Klondike Big Inch Land Co.? It all goes back to oats and land deeds, naturally.

This story starts with a promotional stunt by Quaker Oats in the 1950s that turned into an unexpected collector’s item, worth more today than anyone could have guessed back when “Challenge of the Yukon” echoed in the living rooms across America.

Quaker Oats’ Land Rush Stunt

Back in 1954, in a promotional stunt tied to the radio show “Challenge of the Yukon,” Quaker Oats purchased 19.11 acres of land in the Yukon Territory, the heart of the Klondike Gold Rush region. They cleverly subdivided this acreage into 21 million tiny, one-square-inch plots. Each plot was represented by an official-looking deed. These were created by the Klondike Big Inch Land Co., a company Quaker Oats had established for this purpose.

These miniature deeds were placed inside boxes of Puffed Wheat and Puffed Rice. The campaign was an instant hit. It captured the imaginations of Americans who were thrilled at the notion of owning a piece of the fabled Klondike. Some fans, myself included, collected hundreds of these deeds, aiming to amass a larger piece of the plot.

The Deeds of the Klondike Big Inch Land Co.

The deeds themselves were works of art: elegant green curlicues bordering cream-colored certificates. Each had a stamp with a unique certificate number and an official-looking red seal. An orange map detailed the location of each plot, adding a touch of authenticity and adventure. They promised ownership in a far-off land, albeit only a square inch.

However, the reality was less grand. Quaker Oats never intended these deeds to be legal titles to real estate. They didn’t include mineral rights, and the company didn’t register them. That would have been a logistical nightmare because of the number of deeds issued. Essentially, these deeds were novelties, albeit highly detailed ones.

Despite their questionable legal value, these deeds have become valuable collectibles. Pristine deeds can fetch between $25 and $45 each. This makes the stash of 72 deeds found by a reader potentially worth over $1,800. They represent a unique piece of promotional history, tying back to a time when radio shows were king, and cereal boxes could contain treasures.

The promotion ended, and in 1965, Quaker Oats dissolved the Klondike Big Inch Land Co. The land reverted back to Canada. PepsiCo absorbed Quaker Oats itself in PepsiCo in 2001, but the legend of the Klondike Big Inch lives on among collectors and enthusiasts.

Lessons from a Klondike Big Inch

This episode serves as a fascinating case study in marketing, novelty, and the human penchant for collecting. It also serves as a cautionary tale about the importance of understanding what one truly owns. For those holding these deeds, they own a piece of history, if not a piece of the land.

As a footnote, if you find yourself in possession of such curiosities, consider their historical and collectible value before dismissing them as mere novelties.

 WTF fun facts

Source: “Taking Stock: Decades-old deed to one square inch of Canada’s Yukon Territory has some value” — The Oklahoman

WTF Fun Fact 13747 – Humans Warm up to Tweezer Hands

Apparently, tweezer hands can feel more like part of one’s body than an actual hand.

According to recent research, when it comes to bionic prosthetics, simpler might just be better. A study reveals that people can feel as connected to tweezer-like tools as they do to prosthetic hands that mimic human anatomy—and sometimes even more so.

Rethinking Prosthetics: Function Over Form

At Sapienza University of Rome, cognitive neuroscientist Ottavia Maddaluno and her team are using virtual reality to explore how humans relate to different kinds of prosthetic tools. Their findings may turn some heads—or at least twist some wrists.

The researchers equipped participants with two types of virtual appendages: a realistic human hand and a bionic tool resembling a large pair of tweezers. Through a series of virtual reality tests, they assessed how well subjects could adapt to using these tools in a simulated environment.

Pop Goes the Bubble: Testing Tweezer Hands

Participants engaged in a seemingly simple task: popping virtual bubbles of specific colors. It turned out that those using the tweezer hands completed the task faster and with greater accuracy than those using the virtual human hands. This initial test suggested that the tweezer hands were not only embraced by the participants’ brains but were potentially more effective for certain tasks.

To probe deeper into the subconscious acceptance of these tools, the team employed the cross-modal congruency task. This involved simultaneous tactile vibrations on participants’ fingertips and visual stimuli on the virtual reality screen. The goal was to see how distracted participants were by visual stimuli that did or did not align with the tactile input.

The results were enlightening. Participants generally performed better when the tactile and visual stimuli matched, indicating a strong sense of embodiment for both the tweezer and human hands. However, the tweezer hands showed a more pronounced difference between matched and mismatched trials, suggesting a potentially deeper sense of embodiment.

Simplicity Wins: Why Tweezer Hands Triumph

Maddaluno hypothesizes that the simplicity of the tweezer hands might make it easier for the brain to integrate as part of the body. Unlike the more complex human hand, the straightforward function and design of the tweezers could reduce cognitive load, allowing for quicker acceptance and utilization.

This theory ties into the uncanny valley hypothesis, where things that are eerily similar to human beings but not quite perfect can cause discomfort or unease. The too-real virtual hands might have fallen into this unsettling category, while the clearly non-human tweezers did not.

Practical Applications: The Future of Prosthetics

These insights are not just academic. They have practical implications for the design of prosthetics and robotic tools. If simpler, non-human-like tools can be more readily integrated into a person’s sense of self; they might offer a more effective and acceptable solution for those in need of prosthetic limbs.

Maddaluno’s team is now looking to apply these findings to real-world scenarios, particularly for individuals who have lost limbs. The ultimate goal is to develop prosthetic solutions that are not only functional but also seamlessly integrated into the user’s body image and sense of self.

 WTF fun facts

Source: “People feel more connected to ‘tweezer-like’ bionic tools that don’t resemble human hands” — ScienceDaily

WTF Fun Fact 13746 – More Parking Lots Than Housing

Oddly enough, some cities have gone to such great lengths to accommodate cars that they now have more parking lots than housing!

The city landscape across America reveals a startling fact: in many places, there’s more room for cars than for people. From Seattle to Des Moines, the concrete sprawl of these lots often surpasses the space set aside for housing. This phenomenon isn’t just an urban planner’s nightmare; it’s a real puzzle for anyone trying to find a vibrant city life amidst the vast concrete expanses.

A Concrete Jungle Where There’s More Parking Than Housing

Imagine a city where cars have more room to rest than people do to live. This isn’t a futuristic dystopia; it’s the reality in several U.S. cities where parking lots devour city centers. It turns out we have not only sacrificed urban vitality at the altar of convenience but also transformed downtowns into mere waypoints rather than destinations.

In cities like Seattle, the ratio of parking spaces to housing units is staggering. Seattle boasts about 30 spaces for every acre, overwhelming the number of residential units five to one. Down in Des Moines, the scenario gets more dire with a parking-to-housing ratio of 20 to 1 per acre. These cities, famed for their ever-rising skyscrapers, surprisingly cater more to vehicles than to residents.

The Parking Lot Takeover

The sprawl gets absurd when you head to places like Arlington, Texas, or Detroit, Michigan—cities where the car is king and the pedestrian is a pauper. Arlington’s city center dedicates a whopping 39% of its land to parking. Detroit, the famed Motor City, isn’t far behind, dedicating about a third of its downtown to car spaces. These areas have become so optimized for cars that finding anything else to do can feel like a scavenger hunt.

What’s the big deal, you might ask? Beyond the obvious urban blight, this sea of parking has profound implications. City centers that prioritize parking over accessibility tend to lack the density that makes urban areas vibrant and walkable. The result? Cities that are easy to drive to but not worth staying in. Moreover, this excess of concrete slabs drives up real estate prices, making urban housing scarcer and more expensive.

A Shift Toward More Livable Cities

Despite these challenges, not all cities have succumbed to the parking plague. Washington, D.C., and San Francisco are leading by example, with only 4% and 3% of their downtown areas devoted to public parking, respectively. New York City tops the list with a mere 0.4% of midtown Manhattan given over to parking spaces.

This trend hints at a future where cities reclaim space from cars for people. As more Americans opt out of driving—thanks to the rise of ride-sharing, public transit improvements, and perhaps soon, autonomous vehicles—the demand for vast parking lots is set to decrease. This shift presents a golden opportunity for cities to transform car lots into parks, housing, and vibrant public spaces that foster community rather than car storage.

 WTF fun facts

Source: “These U.S. Cities Have More Parking Lots Than Housing” — Atlas Obscura

WTF Fun Fact 13745 – Can Music Make Food Taste Better?

Can music make your food taste better?

Imagine savoring a plate of spaghetti while Vivaldi’s “Four Seasons” plays softly in the background. Now, could Vivaldi be doing more than just setting the mood? Could it actually make your spaghetti taste better?

Research and some intriguing culinary experiments suggest music might just be the unexpected seasoning we’ve overlooked.

Sonic Seasoning

It’s no secret that a good playlist can enhance a party or a workout, but recent studies show that what you listen to while eating can influence how you perceive flavors. This concept, known as “sonic seasoning,” explores how different sounds can complement or enhance the taste of food. For instance, high pitches might make desserts taste sweeter, while deeper tones could make your steak seem richer.

Back in 2010, a groundbreaking study at Oxford University mapped tastes to musical elements. Researchers found that sweet and sour tastes were often associated with higher pitches, while umami and bitter tastes matched lower ones. Not only that, but certain instruments seemed to evoke specific flavors—brass instruments brought out bitterness, whereas pianos highlighted sweetness.

Culinary Scores to Make Food Taste Better

The idea of combining music with eating isn’t new. Medieval banquets sometimes featured live music alongside feasts, enhancing the sensory experience of dining. Fast forward to the 20th century, the Italian Futurists infused their meals with both music and bizarre theatrics, like their “polyrhythmic salad,” which was eaten while music played from a box turned by a crank.

Even the zany minds behind The Muppet Christmas Carol joked about the notion of “singing food,” a nod to dishes that literally perform as you eat them. And while it sounds like a punchline from a Muppet, the concept has its roots in real historical dining practices where food and entertainment were often intertwined.

Do Beats Bring Out the Flavors?

To see if there’s truth to the science, some food companies are already experimenting with sonic pairings. Barilla, for instance, teamed up with composer Cristobal Tapia de Veer to create the “Al Bronzo Soundtrack Experience.” This is aimed at enhancing the dining experience of specific pasta dishes through tailored musical tracks.

Imagine this: you’re about to fork into some rigatoni. According to Barilla, if you’re listening to twinkling bells and vocal accents, it might just make the cherry tomatoes in your dish taste sweeter and the bacon smokier. It’s a bold claim but one that invites foodies and skeptics alike to put it to the test.

The link between sound and taste might also tie into synesthesia. This is where the stimulation of one sense leads to involuntary experiences in another. Some synesthetes report tasting flavors when they hear certain sounds—a phenomenon that could explain why sonic seasoning might work.

Could it be that we all have a touch of synesthesia that allows us to experience more flavorful meals through the right playlist?

 WTF fun facts

Source: “Can Music Make Your Food Taste Better?” — Atlas Obscura

WTF Fun Fact 13744 – The Capture of Antioch

In the annals of ancient military campaigns, few are as audacious as Khosrow I’s capture of Antioch in 540 AD. Khosrow, the formidable ruler of the Sasanian Empire, didn’t just lead battles; he orchestrated them with the precision of a chess master.

His strategic acumen came to the forefront during the siege and subsequent capture of Antioch, one of the most significant cities of the Byzantine Empire at the time.

Setting the Stage for the Siege of Antioch

Antioch was not just any city. Located on the Orontes River, it was a jewel of the Byzantine Empire, a bustling metropolis known for its grandeur and as a hub of commerce and culture. The idea of capturing such a city was audacious, but Khosrow was not one to shy away from a challenge.

The Sasanian king kicked off his campaign with a well-planned series of maneuvers that caught the Byzantines off guard. His approach was not just about brute force; it was about making a statement. Khosrow wanted to showcase his empire’s might and his capability as a leader.

The Siege That Shook an Empire

When Khosrow’s troops laid siege to Antioch, it was more than just a military blockade. They encircled the city, cutting off all supply lines, and employed a variety of siege tactics that were advanced for the time. The Sasanians used siege towers and battering rams, but also psychological warfare, sowing fear among the city’s defenders.

Despite the city’s strong walls and determined defenders, the relentless siege tactics and the promise of no mercy should resistance continue led to a weakening of the city’s resolve. After a short, albeit intense siege, Antioch fell into Khosrow’s hands. It was a stunning victory that echoed across continents.

Antioch Aftermath

Khosrow’s capture of Antioch was not merely about expanding territory. After taking the city, Khosrow did something unusual: he relocated its population to a new city near his capital of Ctesiphon, which he named Weh Antiok Khosrow, meaning “Khasrow’s Better Antioch.”

This new settlement was a replica of Antioch, complete with similar architectural styles and city planning. This act was a clear message to both his allies and enemies about his power and capability to not just conquer but also to rebuild and repopulate.

Strategic Brilliance and Its Long-term Impact

The capture of Antioch had far-reaching effects. It significantly weakened Byzantine influence in the region and demonstrated the Sasanian capability to strike at the heart of a powerful empire.

The relocation of Antioch’s citizens was a masterstroke in cultural strategy, as it helped to assimilate different peoples into the Sasanian culture, fostering loyalty to Khosrow.

Moreover, this victory and the subsequent treatment of the captured city had long-lasting implications for Byzantine-Sasanian relations. It set the stage for further conflicts but also for periods of peace when mutual respect dictated diplomacy.

 WTF fun facts

Source: “Khosrow I” — Wikipedia

WTF Fun Fact 13743 – Parachuting Beavers

Nope – it’s not a juvenile joke – there really is a story about parachuting beavers. 76 of them, to be exact.

More than seven decades ago, Idaho found itself with a peculiar problem involving beavers too accustomed to urban life. These beavers, having become a nuisance in the growing residential areas, needed new homes. The solution? Parachute them into the wilderness. Yes, you read that correctly: parachuting beavers.

Elmo Heter: The Man with the Plan

Elmo Heter, an officer with Idaho Fish and Game, faced the challenge of relocating beavers from populated areas like McCall, near Payette Lake, to the remote Chamberlain Basin. His ingenious plan involved some old parachutes left over from World War II and a healthy dose of innovation.

Heter knew that transporting beavers by land was fraught with challenges. Horses and mules tended to get spooked by the critters, and driving them through rugged terrain was costly and complex. So, he looked to the skies for an answer.

Dropping Beavers by Plane

Heter devised a method using surplus military parachutes to air-drop beavers into their new wilderness homes. The first task was creating a safe container for the beavers. Initial attempts with woven willow boxes were scrapped when it became apparent that the beavers might chew their way out mid-flight or cause havoc on the plane.

Thus, Heter designed a wooden box that would open upon impact with the ground. To test this innovative container, he chose a plucky male beaver named Geronimo as his first test pilot. Geronimo endured multiple drops to ensure the safety and efficacy of this method.

The Pioneer Parachuting Beaver

Heter dropped Geronimo repeatedly to test the resilience of the box and the beaver’s tolerance. Remarkably, Geronimo adapted well to his role. After numerous trials, he seemed almost eager to get back into his box for another drop. Heter’s plan was proving viable, and soon, it was time to scale up.

Geronimo’s final test flight included a one-way ticket to the Chamberlain Basin, where he joined three female beavers, establishing a new colony in what would become a thriving ecosystem. This land is now part of the protected Frank Church Wilderness.

The Legacy of the Parachuting Beavers

In total, 76 beavers were air-dropped into the wilderness. All but one survived the journey, and they quickly set about doing what beavers do best: building dams and creating habitats that benefit the entire ecosystem. This area is now part of the largest protected roadless forest in the lower 48 states.

The operation, initially seen as a quirky solution, turned out to be a remarkable success, showing that sometimes unconventional problems require unconventional solutions. The savings in manpower and reduction in beaver mortality proved that sometimes, the sky really is the limit.

Why You Won’t See Parachuting Beavers Today

Despite its success, the days of parachuting beavers have passed. Nowadays, the approach to problematic beavers is more about coexistence and less about relocation. The pioneering days of the 1940s, when men like Elmo Heter looked to parachutes to solve ecological challenges, are long gone. Yet, the descendants of those aerial adventurers likely still live on in the Frank Church Wilderness, a testament to one of the most unusual wildlife management efforts ever undertaken.

So, next time you spot a beaver in Idaho, remember that it might just be the descendant of a brave pioneer who once took an unexpected flight into history.

 WTF fun facts

Source: “Parachuting beavers into Idaho’s wilderness? Yes, it really happened” — Boise State Public Radio

WTF Fun Fact 13737 – Putting Animals on Trial

In medieval Europe, people put animals on trial, especially pigs. Yes, you read that right. The judicial system once believed animals could commit crimes. This bizarre practice may sound absurd today, but it was serious business back then.

Animals, like pigs, often roamed freely in villages. When one caused harm, people sought justice through the courts. Imagine a pig munching on someone’s crops or even injuring a child. The villagers would apprehend the offending animal and initiate legal proceedings. They treated these trials like any other criminal case. There were prosecutors, defense attorneys, and judges. The accused animal even had the right to a fair trial.

The Courtroom Drama: Animals in the Dock

During these trials, the courtroom was a spectacle. The animal stood in the dock, just like a human defendant. Lawyers would argue the case, presenting evidence and witnesses. They took their roles seriously, and the trial could draw a crowd of curious onlookers. People saw these trials as a way to maintain order and justice in their communities.

The charges against animals were surprisingly varied. Pigs often faced trial for damaging property or injuring people. But other animals, like cows, goats, and even insects, could also end up in court. Each case followed a similar process, with meticulous attention to legal procedures.

The outcome of these trials could be severe. If found guilty, the animal might face execution or some form of punishment. The authorities believed this would serve as a deterrent, maintaining order and preventing future incidents. It sounds harsh, but people genuinely believed in the efficacy of these measures.

The Peculiar Logic Behind Putting Animals on Trial

So, why did people put animals on trial? The logic was twofold: religious and legal. On the religious side, people believed animals, like humans, could sin. The church taught that animals, if possessed by evil spirits, could act against humans. Hence, trials served as a means to address this spiritual imbalance.

Legally, animals had a form of personhood. Medieval law extended some human rights to animals, holding them accountable for their actions. This perspective was strange but consistent with the period’s worldview. The legal system aimed to uphold societal norms and ensure justice, even if it meant trying a pig.

Interestingly, these trials also provided a form of catharsis for the community. By holding a public trial, people could vent their frustrations and seek closure. It was a way to address grievances and restore peace in the village.

Modern Reflections on Medieval Animal Trials

Today, the idea of putting animals on trial seems absurd and unjust. Our legal system recognizes animals as non-human entities, not capable of intent or guilt. We understand that animals act on instinct, not malice. This shift in perspective reflects broader changes in our understanding of justice and animal behavior.

So, the next time you see a pig, remember its ancestors might have faced a judge and jury. And be glad we’ve moved on from such peculiar practices. Justice today looks a lot different, and for good reason. We’ve learned that blaming animals for their actions doesn’t quite hold up in court.

 WTF fun facts

Source: “When Societies Put Animals on Trial” — JSTOR Daily

WTF Fun Fact 13736 – We Turn Down the Music to Find Things

Ever noticed how you instinctively turn down the music in your car when searching for an address or navigating a tricky intersection? This common behavior might seem odd at first glance, but it actually makes a lot of sense. The act of lowering the volume to focus on a visual task taps into some fundamental aspects of how our brains process information.

Humans rely on their cognitive resources to manage and interpret sensory input. When driving, we constantly process visual, auditory, and sometimes tactile information. Turning down the music helps free up cognitive resources, allowing us to focus more effectively on the visual task at hand.

The Science Behind Turning Down the Music

Our brains have a limited capacity for processing information. Known as cognitive load, this concept refers to the amount of mental effort being used in the working memory. High cognitive load can impair our ability to process new information or perform complex tasks.

When the music is blaring, it adds to the cognitive load by demanding attention.

This auditory input competes with visual and spatial processing, making it harder to concentrate on tasks like reading street signs or spotting a turn. Lowering the volume reduces the cognitive load, allowing the brain to allocate more resources to visual processing.

Studies have shown that multitasking, especially with tasks that require different types of sensory input, can significantly reduce performance. For example, trying to listen to a conversation while reading a map can overwhelm the brain’s processing capabilities. Turning down the music minimizes this interference, making it easier to focus on the visual task.

Sensory Overload and Attention

Sensory overload occurs when one or more of the body’s senses experience over-stimulation from the environment. This can happen when there are too many sounds, sights, or other sensory inputs at once. In a car, loud music can contribute to sensory overload, making it difficult to focus on navigating or searching for an address.

Attention, a crucial component of cognitive function, can be divided into different types. Selective attention involves focusing on a particular object or task while ignoring irrelevant information. When we turn down the music, we enhance our selective attention toward the visual task, filtering out unnecessary auditory distractions.

Moreover, the brain’s executive functions, which include planning, decision-making, and problem-solving, play a significant role in driving and navigating. These functions are more effective when not competing with high levels of background noise. Lowering the music volume helps these executive functions operate more efficiently.

Practical Implications

Understanding why we turn down the music when looking for something can have practical applications beyond driving. This behavior highlights the importance of managing cognitive load and sensory input in various settings. For instance, in workplaces or study environments, minimizing background noise can enhance concentration and productivity.

In educational settings, reducing auditory distractions can help students focus better on visual learning materials. Similarly, in open-plan offices, creating quiet zones or using noise-canceling tools can improve employee focus and performance. These strategies are grounded in the same principles that lead us to lower the car’s music volume when searching for an address.

 WTF fun facts

Source: “Why Do We Turn Down the Radio When We’re Lost?” — How Stuff Works