Health

Find some great and fun health facts all gathered right here under our health category.  Once you have had your fill of fun facts about health head on over to our random fact generator to learn more random factoids!

WTF Fun Fact 13591 – The Grandmother Hypothesis

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Have you heard of the grandmother hypothesis? Basically, it means grandma was right about washing behind your ears!

When it comes to maintaining skin health, certain regions, like behind the ears and between the toes, often get overlooked. Research by the George Washington University reveals why paying attention to these areas is essential. The skin microbiome, which refers to the collection of microbes residing on our skin, has shown variation in composition across different skin regions, be it dry, moist, or oily.

Exploring the Grandmother Hypothesis

The GW Computational Biology Institute set out to explore the widely accepted but scientifically unproven “Grandmother Hypothesis.” Keith Crandall, Director of the Computational Biology Institute, recalls the age-old advice from grandmothers: always scrub behind the ears, between the toes, and inside the belly button. But why? The belief is that these less frequently washed areas might house different bacterial compositions compared to more regularly scrubbed parts of the body.

To put this to the test, Marcos Pérez-Losada and Keith Crandall designed a unique genomics course, involving 129 graduate and undergraduate students. These students collected data by swabbing areas like behind their ears, between their toes, and their navels. For comparison, samples were also taken from drier regions such as calves and forearms.

Revealing Differences in Microbial Diversity

The results were enlightening. Forearms and calves, often cleaned more diligently during baths, displayed a broader and presumably healthier range of microbes. This is compared to hotspots like behind the ears and between the toes. A balanced skin microbiome is essential for skin health. A dominance of harmful microbes can disrupt this balance, potentially leading to skin conditions such as eczema or acne.

The study’s outcomes suggest that cleaning habits indeed impact the microbial population on the skin, further influencing its health. Thus, the age-old advice from our grandparents holds some truth after all!

Implications of the Grandmother Hypothesis

The research carried out by the GW Computational Biology Institute provides significant insights into the skin microbiome of healthy adults. It serves as a benchmark for future studies. There is still a long way to go in understanding the intricacies of how the microbial community on our skin impacts our overall health or disease state.

The study titled “Spatial diversity of the skin bacteriome” marked an essential milestone in the field. It sheds light on the diverse bacterial communities residing in different parts of our skin. Published in the renowned journal Frontiers in Microbiology on September 19, it is a stepping stone to further research in this rapidly evolving domain.

In conclusion, paying heed to the lesser-focused regions of our skin, as our ancestors advised, might be the key to ensuring a balanced and healthy skin microbiome. So next time you shower, remember to scrub those often-neglected areas!

— WTF fun facts

Source: “Skin behind the ears and between the toes can host a collection of unhealthy microbes” — ScienceDaily

WTF Fun Fact 13589 – A Voice Test for Diabetes

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If you’re scared of needles, you might be interested to know that researchers are investigating a possible voice test for diabetes.

That’s right. A brief recording of your voice could indicate whether or not you have diabetes.

A Voice Test for Diabetes?

A program designed to use no more than 10 seconds of speech has proven capable of identifying the presence of diabetes with remarkable accuracy.

In an experiment conducted by Klick Labs, 267 individuals recorded a short phrase on their smartphones six times a day over a span of two weeks. This group had recently undergone testing for Type 2 diabetes. The aim? To discern any acoustic differences between the voices of those who tested positive and those who didn’t.

By analyzing the participants’ voice prints in conjunction with data like age, sex, height, and weight, an AI model made astonishing predictions. The accuracy rate stood at 86% for men and an even higher 89% for women.

Unraveling the Science Behind Voice Analysis

The question arises: Why does diabetes influence one’s voice? The synthesis of our voice is a multifaceted process that integrates the respiratory system, nervous system, and the larynx. Factors that impact any of these systems can, in turn, alter the voice. While such changes might escape the human ear, computers, with their advanced analytical capacities, can detect them with precision.

Among the vocal attributes studied, pitch and its variation proved to be the most predictive of diabetes. Interestingly, some vocal attributes only enhanced prediction accuracy for one gender. For instance, “perturbation jitter” was a key factor for women, whereas “amplitude perturbation quotient shimmer” was significant for men.

It’s worth noting that prolonged elevated blood sugar can impair peripheral nerves and muscle fibers, leading to voice disorders. Moreover, even temporary elevations in blood glucose can potentially influence vocal cord elasticity, though this theory still awaits validation. Furthermore, emotional factors, such as anxiety and depression—both of which can be associated with diabetes—may further modulate voice characteristics.

Beyond Conventional Diabetes Testing

Jaycee Kaufman, the leading author of the study, emphasized the transformative potential of their findings: “Voice technology can potentially revolutionize the way the medical community screens for diabetes. Traditional detection methods can be cumbersome, both in terms of time and cost. This technology could eliminate these challenges altogether.”

Considering the global surge in diabetes cases, and the complications arising from late diagnoses, the introduction of a non-invasive, rapid testing tool can be a game-changer. The International Diabetes Federation has highlighted that nearly 50% of adults with diabetes remain unaware of their condition. Predictably, this unawareness is most pronounced in nations where healthcare infrastructure is stretched thin. The economic implications are staggering, with undiagnosed diabetes projected to cost an exorbitant $2.1 trillion annually by 2030.

Voice technology, as an alternative to blood sample-based tests, presents a promising avenue for early detection and intervention.

A Healthier Future Using A Voice Test for Diabetes

Buoyed by the success of their study, Klick Labs is planning a larger-scale project. They aim not only to refine the accuracy of their model but also to expand its scope. Their vision extends beyond diabetes detection, as they explore its applicability to conditions like prediabetes and hypertension.

Yan Fossat, co-author of the study, expressed enthusiasm for the innovation: “Voice technology has the potential to usher in a new era in healthcare, positioning itself as a vital digital screening tool that’s both accessible and economical.”

As the study gains traction and the technology evolves, the implications for global health are profound. With the power of voice technology, a world where early, easy, and efficient disease detection is the norm, may not be too far off.

—WTF fun facts

Source: “10 Seconds Of Recorded Speech Can Reveal If Someone Has Diabetes” — IFL Science

WTF Fun Fact 13580 – Deadliest Heart Attacks on Monday

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Heart attacks on Monday seem to be a recurring theme. Recent findings suggest that, for some reason, people are more likely to face life-threatening heart issues as the new week kicks off. Let’s dive into what the research says and why this might be happening.

The Monday Mystery

A big conference in Manchester brought some surprising news to the table. Medical experts from Belfast and Ireland checked out hospital data for over 10,000 patients from 2013 to 2018. They found that a very serious type of heart attack, called STEMI, was more common on Mondays. Basically, STEMI is when a main blood vessel to the heart gets fully blocked. If doctors don’t treat it fast, it can be deadly.

Now, every year, around 30,000 people in the UK end up in the hospital because of STEMI. They get a quick check and usually undergo a procedure to unblock the vessel and get blood pumping properly again. What’s odd is that this research found Mondays had a 13% higher chance of people coming in with this problem. Even Sundays had a bit of a bump.

But why Mondays? Well, that’s the big question. Some older studies think our body’s natural sleep-wake cycle might play a role. But the full picture isn’t clear yet.

Doctors Weigh in on Heart Attacks on Monday

Dr. Jack Laffan, who headed the study, admits that this Monday trend is curious. He thinks several factors might be at play. One idea is our body’s natural clock. Our sleep patterns, wake-up times, and daily habits could influence when heart attacks happen.

Meanwhile, another expert, Professor Sir Nilesh Samani, stresses the importance of these findings. Heart attacks are always a medical emergency, no matter the day. He believes that the more we learn about the “Monday effect”, the better doctors can prepare and save more lives.

In the end, while Mondays might have a higher rate of heart attacks, every day is important when it comes to heart health. Whether it’s stress from starting a new work week or something else entirely, the research continues. The goal is always to protect our hearts and understand what might put them at risk.

—WTF fun facts

Source: “Why are serious heart attacks more likely on a Monday?” — British Heart Foundation

WTF Fun Fact 13574 – Katalin Karikó

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Katalin Karikó’s journey to Nobel glory is one of resilience and steadfast dedication. A biochemist, Karikó had always been keen on exploring the therapeutic potentials of mRNA.

She obtained her PhD from Hungary’s esteemed Szeged University in 1982 and secured a tenure-track professor position at the University of Pennsylvania in 1989. But her research into RNA faced numerous challenges.

Funding eluded her, and her experiments saw little success. The 1990s brought more trials. This included a cancer diagnosis, the choice to abandon her research or accept a demotion, and a pay cut. She chose the latter, demonstrating her unyielding commitment to mRNA’s potential.

Katalin Karikó”s Partnership with Weissman

1997 marked a turning point. Immunologist Drew Weissman joined the University of Pennsylvania and partnered with Karikó. His interest lay in developing an HIV vaccine. The goal was to prime immune responses with dendritic cells, known for training T cells against foreign antigens. Their collaboration led to the discovery that synthetic, unmodified mRNA provoked dendritic cells into activating inflammatory responses.

The duo’s realization that mammalian cell RNA was frequently chemically modified (while bacterial DNA and RNA often weren’t) changed the course of their research. Another significant insight was that toll-like receptors (TLRs) specifically detected DNA and RNA modifications to trigger inflammation. Their 2005 research paper unveiled that synthetic RNA activated several TLRs, causing inflammatory responses. But adding specific modifications to the synthetic mRNA’s bases curtailed these responses and even enhanced protein production.

mRNA Shaping Modern Vaccine Production

This groundbreaking work ushered in the era of mRNA therapeutics. It catalyzed the inception of Moderna and BioNTech, the companies that later formulated the lifesaving mRNA COVID-19 vaccines. A testament to Karikó and Weissman’s work is the modified base m1 Ψ, now integral to Moderna and Pfizer-BioNTech’s vaccine production.

Recognition Overlooked Despite the promise and subsequent success of her research, Karikó’s contributions remained largely overshadowed. The scientific community’s initial apathy was evident: post their 2005 revelation, Karikó revealed a lack of interest from peers and major biopharma companies. By 2013, this disregard culminated in her departure from the University of Pennsylvania. Yet, adversity wasn’t new to her. Rather than be deterred, she associated with BioNTech, ascending from hands-on benchwork to senior vice presidency. In 2021, she returned to academia, serving at Szeged University and as adjunct faculty at UPenn. Meanwhile, Weissman continued at UPenn, helming the Penn Institute for RNA Innovations.

Katalin Karikó and Nobel Acclaim

The Nobel Prize in Physiology or Medicine awarded to Karikó and Weissman celebrates their persistent, pioneering work on mRNA technology. This research directly paved the way for the creation of the frontrunner COVID-19 vaccines. It’s a fitting tribute to Karikó, who faced professional setbacks and health challenges, yet never deviated from her belief in mRNA’s potential. For her, the Nobel isn’t just an award—it’s validation of decades of unwavering commitment.

The story of Katalin Karikó story serves as an inspiring lesson on perseverance. Her Nobel win, alongside Drew Weissman, underscores the importance of dedication to scientific exploration, even in the face of skepticism and adversity. Their work expanded our understanding of mRNA and provided the foundation for life-saving vaccines during a global pandemic.

—WTF fun facts

Source: “After being demoted and forced to retire, mRNA researcher wins Nobel” — Ars Technica

WTF Fun Fact 13565 – A Way To Regrow Teeth?

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Many of us grapple with tooth loss after an injury or other dental issue – so wouldn’t it be nice if, instead of paying thousands of dollars for a porcelain replacement, scientists found a way to help us regrow teeth?

Well, we’re getting closer!

Researchers from the University of Plymouth have made groundbreaking progress, unveiling a gene that may hold the secret to tooth regeneration.

The Power of Stem Cells

Historically, stem cells have been the beacon of hope in understanding and treating many diseases. That’s because they hold unparalleled potential by being capable of transforming into almost any cell type the body might need. Whether it’s forming new blood cells or rejuvenating bone cells, stem cells are invaluable in helping us recover and regenerate.

It’s no wonder, then, that scientists often harvest stem cells from youthful sources like primary teeth or wisdom teeth. Simply put, younger cells teem with vitality, making them robust candidates for regenerative medicine.

Stem cell therapy has, over the years, provided relief to patients battling conditions ranging from Alzheimer’s and diabetes to multiple sclerosis.

However, only recently have scientists honed in on how stem cells can revolutionize dental health.

Revolutionary Findings to Help Regrow Teeth

Dr. Bing Hu of the Peninsula Dental School at the University of Plymouth and his global team of scientists have uncovered a game-changing revelation: the Dlk1 gene. This gene seems to be the catalyst for enhanced stem cell activation and tissue renewal.

Their journey began with the discovery of a previously unknown group of stem cells in mouse incisors.

Typically found in muscles and bones, these mesenchymal cells spring into action when exposed to the Dlk1 gene. The result? An increased production of dentin – a crucial component in teeth.

Even more impressive was Dlk1’s ability to regenerate tissues in mice with dental injuries.

Future Implications

Of course, with all major discoveries come the caveats. Dr. Hu emphasizes the importance of further studies to cement their initial findings. Yet, he remains optimistic about transitioning from animal models to human trials soon.

This research is a beacon of hope for those who have struggled financially to have lost teeth replaced. Imagine a future where dental procedures are not only more efficient but also more affordable. A future where losing a tooth doesn’t spell permanent loss, but a temporary inconvenience.

While the Plymouth team’s findings are revolutionary, they aren’t the first to tread this path. Back in 2021, a study from Japan revealed the potential of targeting genes to regrow teeth in animals. Their focus? The USAG-1 gene. Fast forward to today, and this Japanese team is setting the stage for a 2024 clinical trial, targeting tooth regeneration in humans.

If all goes well, by 2030, we might be ushering in a new era of dental care.

—WTF fun facts

Source: “Humans Have a Third Set of Teeth. New Medicine May Help Them Grow” — Popular Mechanics and “Scientists Discover New Gene That Can Help Repair Teeth” — Today’s RDH

WTF Fun Fact 13558 – Mental Imagery

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Teenagers are often vulnerable to spirals of negative thoughts, but new research suggests a possible solution: mental imagery.

The Study on Mental Imagery for Teens

Oregon State’s Hannah Lawrence, an assistant professor of psychology, spearheaded the study. The results indicated that shifting focus to mental imagery acts is a strong distractor. In fact, it’s more of a distraction than simple verbal thoughts for adolescents trapped in negative ruminations.

Lawrence’s insights shine a light on a significant issue. Drowning in past regrets not only deepens one’s sorrow but also makes emotional regulation a greater challenge.

Introducing brief diversions, especially in the form of mental imagery, offers a momentary break from these cyclic patterns. This could potentially facilitate a bridge to more extensive help through therapy, familial support, or friendships.

Experiment Procedure

Published in the Journal of Affective Disorders, the research aimed to contrast the impact of verbal thoughts and imagery-based thoughts on the general mood of adolescent participants.

The study encompassed 145 participants, aged 13 to 17, predominantly white, with 62% females. These individuals were from a rural New England area. A striking 39% displayed symptoms consistent with clinical depression.

The mood-setting phase involved an online game, inducing feelings of exclusion among the participants. Subsequently, they were divided into groups, engaging in either rumination or distraction exercises using either verbal or imagery-based prompts.

For rumination, a prompt might be “Imagine the kind of person you think you should be.” For distraction, it could be as mundane as “Think about your grocery list.”

Key Findings on the Power of Mental Imagery

The research found that both forms of rumination (verbal and imagery) affected the participants’ moods similarly. However, mental imagery stood out as a more potent form of distraction.

Lawrence noted, “Using mental imagery seems to help us improve our affect, as well as regulate our nervous system.” The form of negative thoughts, be it verbal or visual, may not matter as much as the relentless focus on distressing matters.

The potency of mental imagery is still not entirely understood. It may be the case that imagery demands more effort and is more immersive. Therefore, it elicits stronger emotional responses, thus serving as a better distraction.

There’s also evidence suggesting that visualizing mental images activates the same brain regions as witnessing those events firsthand.

The Evolution of Rumination

Lawrence has observed that while some adults stick to one form of rumination, most teenagers report employing both verbal thoughts and mental imagery. These patterns might solidify over time, becoming habitual and reinforcing the negative imagery or messages.

Lawrence highlights the crucial nature of her work with teenagers, expressing her hope that early interventions can help these youngsters navigate to adulthood without being tethered to detrimental thought patterns.

—WTF fun facts

Source: “Mental imagery a helpful way to distract teens from negative thought patterns” — Science Daily

WTF Fun Fact 13557 – Lucid Dying

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A groundbreaking study spearheaded by NYU Grossman School of Medicine explored the concept of “lucid dying” and dives deeper into what is termed as “lucid death experiences.”

Lucid dying refers to the vivid, clear, and conscious experiences that some cardiac arrest survivors recall having when they were supposedly unconscious. The study involved 567 patients. Fewer than 10% made a sufficient recovery after CPR to leave the hospital. But the survivors had some fascinating stories to share. Four 4 out of every 10 of these survivors remembered experiencing some degree of consciousness during CPR.

What the Brain Shows During Lucid Dying

Advanced brain monitoring techniques provide a more in-depth look into what happens during these moments. For some patients, nearly 40% displayed brain activity reverting to normal, or close to normal, even an hour into CPR from a previously “flatline” state. This was measured using EEG technology, a tool that traces brain activity. These patients exhibited spikes in brain waves linked to higher cognitive functions.

Survivors have historically spoken of heightened awareness and potent, lucid experiences during near-death moments. They’ve described sensations such as detaching from their bodies, painlessly observing events, and conducting profound assessments of their actions and relationships throughout their lives. The study emphasizes that these are not mere hallucinations, delusions, or dreams. Instead, they appear distinct from such states and even differ from CPR-induced consciousness.

Why Does This Happen?

Researchers propose that as the brain approaches a “flatlined” state, its natural inhibitory systems get deactivated. This phenomenon is termed disinhibition.

This might grant access to “new dimensions of reality.” These could include vivid memories spanning one’s entire life, seen through a moral lens. The evolutionary reason behind such experiences remains unknown. Still, the fact that they happen prompts further investigation into the mysteries of the human mind and the event of dying.

Clinical Implications of Lucid Dying

Most doctors believe that the brain endures irreversible damage approximately 10 minutes after the heart stops supplying oxygen. However, this research demonstrates the potential for the brain to show signs of electrical recovery well into the CPR process.

Such findings suggest that these recalled experiences and changes in brain waves could be hallmarks of universal elements in so-called near-death situations.

Dr. Sam Parnia, the lead researcher of the study, had an interesting perspective. He noted, “These experiences provide a glimpse into a real, yet little understood dimension of human consciousness that becomes uncovered with death.”

Such insights could lead to innovative methods to restart the heart. They might also help prevent potential brain injuries, or have implications in transplantation procedures.

The AWARE-II Study

The AWAreness during REsuscitation (AWARE)-II study, involved observing 567 individuals who suffered cardiac arrests during their hospitalizations between 2017 and 2020 across the US and UK. By only enrolling hospitalized patients, the study ensured standardized CPR, resuscitation, and brain activity recording methods. A fraction of these patients, 85 in number, underwent brain monitoring throughout their CPR.

Additionally, the testimonies of 126 survivors from the community who remembered their experiences of death were also scrutinized. These helped provide a broader perspective on the themes tied to the recollection of dying.

The research brings up fascinating new hypotheses about lucid dying. But it neither confirms nor refutes the validity or implications of patients’ experiences and awareness during their brushes with death. However, these experiences surrounding death are deemed worthy of more exhaustive scientific investigation.

Future studies may aim to pinpoint biomarkers of clinical consciousness and observe the prolonged psychological aftermath of being resuscitated post-cardiac arrest.

—WTF fun facts

Source: “New evidence indicates patients recall death experiences after cardiac arrest” — Science Daily

WTF Fun Fact 13554 – The Most Dangerous Jobs

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When we think of the most dangerous jobs, our minds often drift to high-action roles, like police officers or firefighters. However, statistical data paints a different, more nuanced picture.

It’s not uncommon to hear discussions about the perils of patrolling the streets. However, data from the U.S. Bureau of Labor Statistics (BLS) sheds light on the occupations that statistically face higher risks daily, and they might not be the ones you’re thinking of.

The Real Most Dangerous Jobs in America

Various blue-collar roles often go unnoticed in their level of peril.

For example, mechanics – both supervisors and those specializing in heavy vehicles – face significant challenges in their workplaces. Heavy vehicle mechanics, dealing with substantial machinery like bulldozers and tractors, confront transportation incidents frequently, with many hazards stemming from the machines they’re entrusted to service.

It’s not just the machinery-oriented jobs that bear these dangers. Those who maintain our public and private spaces, grounds maintenance workers, also navigate risks. Their tasks might appear benign – manicuring lawns, trimming trees, and tending to parks – but their fatal injury rate is on par with heavy vehicle mechanics. Surprisingly, transportation incidents are their predominant threat.

Moreover, general maintenance workers and construction laborers experience considerable hazards. Accidental contact with objects, equipment malfunctions, and falls from significant heights are everyday threats they navigate, often without the same public acknowledgment of their risks.

Perspective on Peril

When juxtaposed with police officers’ fatal injury rate of 14 per 100,000 workers, it becomes evident that several other occupations face equal or even greater threats. The BLS data brings forth an intriguing perspective: while the dangers of law enforcement are well-publicized and recognized, many other workers face similar or heightened risks in relative obscurity.

So the real most dangerous jobs?

  • Logging workers
  • Airline pilot and flight engineers
  • Derrick operators in oil and gas
  • Roofers
  • Garbage collectors
  • Iron workers
  • Delivery drivers
  • Farmers

Even crossing guards rank higher on the deadly jobs list than police officers, which come in at #22. And it’s not that having the 22nd most dangerous job isn’t dangerous – it certainly is. The issue is we don’t often appreciate the extent to which the people who collect our trash or deliver our packages also put their lives on the line every day when they head to work.

Behind the Numbers

The BLS’s Census of Fatal Occupational Injuries is a treasure trove for understanding the nuances of workplace fatalities. This analysis spotlighted 263 professions, each boasting a workforce of at least 50,000 individuals.

To determine the fatal injury rate, fatalities were compared to the number of roles in that occupation. The average from 2014-2018 was then calculated to minimize the influence of yearly variations.

Information regarding the predominant causes of fatal accidents was extracted from this comprehensive census. Simultaneously, salary insights came from the Occupational Employment Statistics Survey.

Recognizing the latent dangers in these professions accentuates the importance of proper safety training and practices. It’s important to acknowledge the sacrifices and challenges faced by these unsung heroes in our everyday lives.

So, the next time you see a mechanic working under a vehicle, a roofer working on a house, or your local trash collector, take a moment to appreciate their dedication and the risks they take daily.

—WTF fun facts

Source: “Top 25 most dangerous jobs in the United States” — Industrial Safety and Hygiene News

WTF Fun Fact 13539 – Male Menstruation in Egypt

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While male menstruation sounds like an anomaly, accounts from Egypt painted a curious picture.

During the Napoleonic campaigns in the early 19th century, French soldiers noted a peculiar condition among the local Egyptian men: many reported blood in their urine, leading to the label “the land of the menstruating men.”

Deciphering Male Menstruation

The actual cause behind this perplexing phenomenon is a parasitic disease named schistosomiasis. It originates from Schistosoma worms.

When freshwater snails infected with these parasites release larvae, those larvae can penetrate the skin of humans who come into contact with the water.

Once the larvae invade a human host, they mature into adult worms that live in the blood vessels. The female worms lay eggs, some of which the body excretes through urine or feces, and some remain in the body.

It’s these eggs that can cause inflammation, tissue damage, and bleeding when they lodge in the bladder or intestine.

The presence of blood in urine, or hematuria, became a characteristic symptom among many Egyptian men. This sign of schistosomiasis was the source of the “male menstruation” confusion.

The disease not only caused physical distress but also carried a significant cultural and psychological burden given the societal perceptions of the symptoms.

French Soldiers and Schistosomiasis

In the late 18th century, under the leadership of Napoleon Bonaparte, French ambitions extended beyond Europe, aiming to challenge the British Empire’s growing dominance.

The French campaign in Egypt, which began in 1798, was a strategic endeavor to disrupt British trade routes to India and spread revolutionary ideals. Napoleon, with an army of approximately 35,000 soldiers, invaded Egypt, capturing Alexandria and later Cairo.

This expedition was not purely military; it also included scholars and scientists who studied the ancient and contemporary culture of Egypt. Their presence led to significant discoveries, including the famed Rosetta Stone.

However, while the campaign had initial successes, it faced challenges, such as an encounter with schistosomiasis.

While the local Egyptians bore the “menstruating men” moniker, the French soldiers were not immune. Many who waded in the Nile for bathing or other activities also contracted the disease. However, the term likely stuck more with the Egyptians due to pre-existing observations.

Unraveling the Mystery of Menstruating Men

It took some time before medical professionals connected the dots. The visible blood in urine, a clear symptom of a severe schistosomiasis infection, was initially misunderstood. (However, both men and women suffered from this symptom.)

Eventually, with advancements in medical knowledge and further studies in parasitology, the real nature of the disease became apparent. Scientists and doctors recognized that the “male menstruation” was actually a manifestation of schistosomiasis.

Modern medicine offers effective treatments for schistosomiasis, primarily using the drug praziquantel. Efforts to control the disease also focus on reducing the population of infected snails and improving sanitation to prevent contamination of freshwater sources. Education campaigns aim to reduce human contact with infested water.

Today, the disease remains endemic in many parts of Africa, including Egypt, but global health initiatives strive to reduce its impact.

Recognizing the history and myths surrounding schistosomiasis can help in understanding its cultural implications and the importance of continued efforts to combat it.

—WTF fun facts

Source: “History of schistosomiasis (bilharziasis) in humans: from Egyptian medical papyri to molecular biology on mummies” — Pathogens and Global Health

WTF Fun Fact 13495 – Haunted House Carbon Monoxide Theory

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The haunted house carbon monoxide theory takes a little bit of the ghoulishness out of Halloween. But it its place is something much scarier. Those ghosts might be a sign that you’re being poisoned!

Now, we’re not talking about the haunted houses that you go to for Halloween fun. We’re talking about people who actually feel and hear and see ghosts that they think are coming from beyond the grave.

What’s the Haunted House Carbon Monoxide Theory?

There’s a saying: “When you hear hoofbeats, think horses, not zebras.” Yet, when it comes to stories of haunted houses, the supernatural often takes precedence over the logical.

Such tales have captivated our imagination for centuries, with eerie apparitions, whispered voices, and otherworldly sensations. But could there be a more down-to-earth explanation for these ghostly experiences?

Enter carbon monoxide.

Carbon monoxide (CO) is a colorless, odorless gas that can cause a wide range of health problems and even death when inhaled in large amounts. It affects the body by preventing oxygen from entering cells and tissues, leading to a condition called hypoxia.

The Unusual Cases of “Hauntings”

There’s been a growing awareness of how carbon monoxide poisoning can cause symptoms eerily similar to those described in paranormal encounters.

Take the example from an American Journal of Ophthalmology report from 1921. A family started seeing apparitions and experiencing a constant sensation of being watched. The children lost interest in play, became ill, and the father even witnessed a mysterious woman in black. The mother, too, had her own harrowing encounters. (This example is cited in IFL Science, cited below).

It wasn’t until the father’s brother suggested a more rational cause that the mystery was solved: carbon monoxide poisoning, originating from a broken furnace.

Writer Carrie Poppy described an unnerving presence in her house, complete with auditory hallucinations and a peculiar pressure on her chest to to NPR (via IFL Science). She felt watched and perceived an ominous “whoosh” sound. To her, this was no mere haunting; she believed a demon occupied her home.

The distress became so overwhelming that she found herself in tears nightly. However, a group of skeptical ghost hunters steered her towards a more plausible explanation: carbon monoxide. And sure enough, a gas leak was identified as the root cause.

Haunted Houses and Carbon Monoxide: A Tale Of Ghosts and Gas Lamps?

There’s an intriguing theory that the Victorian era, known for its plethora of ghost stories and an intense fascination with the supernatural, might have had a carbon monoxide connection.

Toxicologist Albert Donnay suggests that carbon monoxide and other toxins could be responsible for a large number of these hauntings.

The Victorians, with their gas lamps and toxic wallpaper, could have inadvertently been subjecting themselves to low doses of poison, leading to hallucinations and the perception of hauntings.

A Logical Explanation in a Paranormal World

While it’s true that not every ghostly encounter can be chalked up to carbon monoxide — some might be hoaxes, products of sleep paralysis, or even crafty hotel managers attempting to boost business — it’s essential to consider the possibility. Often, the answers we seek lie not in the realm of the otherworldly, but in the tangible world around us.

In essence, if you believe you’ve encountered a spectral presence or feel like something’s not quite right in your home, it might not be a ghostly visitor. Instead, it could be a silent and deadly gas.

So, before calling in the paranormal investigators, IFL Science writer Andrew Felton suggests you ring up a technician to inspect your home’s heating system. Your “haunting” might just be a malfunctioning boiler or furnace.

—WTF fun facts

Source: “An Awful Lot Of Hauntings Can Be Attributed To Carbon Monoxide Poisoning” — IFL Science

WTF Fun Fact 13492 – Information Seeking Behavior

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Normally, when we think of smartphone addiction, we think of video games or social media, but information-seeking behavior, such as constantly scrolling through the news, can be hazardous to your health as well.

In our digital age, many people often hear notifications, see never-ending news feeds, and feel the pull to browse news apps daily. This behavior ties into our brain chemistry. Dopamine, a key neurotransmitter, drives our desire to seek information and rewards.

The Role of Dopamine in Information-Seeking Behavior

People often call dopamine the “feel-good” chemical. But it’s better to think of it as a messenger for reward-seeking, motivation, and pleasure. When we experience something pleasurable, our brain releases dopamine. This makes us want to repeat that action.

In the past, dopamine helped us survive. For instance, when our ancestors found food or water, a dopamine rush would push them to keep searching for these essentials.

Why We Seek Information

As societies evolved, so did our dopamine triggers. Now, our brain doesn’t only release dopamine for physical rewards but also for intangible ones like information. Discovering new information gives our brain a dopamine boost. Historically, this made sense. Early humans needed new knowledge for survival, like learning about potential dangers.

Today, each piece of news or an article can trigger dopamine, making us crave more. It’s like how we yearn for food or other activities that make us feel good.

Smartphones: Dopamine Machines

Smartphones and apps capitalize on our dopamine system. Every swipe or notification can be a dopamine rush. The element of surprise—whether the next swipe reveals a meme, a news update, or a message—boosts our dopamine even more.

This unpredictability mirrors slot machines. You never know when you’ll hit the jackpot, making you play more. Likewise, not knowing what the next notification holds keeps us glued to our screens.

However, too much dopamine has its downsides. Over time, frequent dopamine hits from constant scrolling can dull our response. Like how drug users need more drugs over time, we might need more screen time or new information for the same dopamine kick.

This never-ending search for information can overload us. We might struggle to understand or remember what we read. We can even feel mentally exhausted.

Balancing Out Information Seeking Behavior

Knowing dopamine’s role in our online habits can help us use tech wisely. Here’s how:

  • Set Limits: Designate times for browsing news or social media. This reduces the impulse to always check for news.
  • Take Digital Breaks: Stepping away from screens occasionally can help reset our brain’s dopamine response.
  • Choose Wisely: Don’t just scroll. Engage deeply with a few key topics.
  • Control Notifications: Fewer non-urgent notifications mean fewer urges to check your device.

Our relationship with dopamine and information seeking shines a light on our tech habits. Technology offers us endless information, but understanding the dopamine effect helps us use it wisely. By realizing how our brains work in this digital era, we can enjoy tech without letting it control us.

—WTF fun facts

Source: “The Dopamine Seeking-Reward Loop” — Psychology Today

WTF Fun Fact 13491 – Loneliness Kills

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We can all think of a long list of stuff that’s bad for our health – but did you know loneliness kills as well?

Loneliness Kills in the Age of Connectivity

The dangers of smoking have been widely acknowledged and documented for years. From lung cancer to heart diseases, the repercussions of this habit are severe. Yet, there’s another rising health concern that many might not associate with physical harm: loneliness. Recent studies are revealing that the health risks of prolonged isolation might be as detrimental as smoking.

Ironically, we live in an era termed the “age of connectivity.” Technology has bridged continents, enabling face-to-face conversations without the need for physical proximity. Yet, as we increasingly immerse ourselves in the digital world, it seems we’re drifting apart in the real one. This paradox is contributing to what experts now call an “epidemic of loneliness.”

Loneliness vs. Being Alone

It’s vital to understand that loneliness and being alone aren’t synonymous. One can feel lonely in a crowded room, while another might cherish solitude without feeling isolated. Loneliness is the subjective feeling of being isolated, regardless of the actual social situation.

Loneliness does not merely affect mental well-being; it has severe physical repercussions. Just like smoking, prolonged feelings of isolation can lead to an array of health complications:

  1. Cardiovascular Issues: Loneliness can increase the risk of heart diseases. A lack of social connection has been found to be a significant factor in heart attacks, strokes, and other cardiovascular events.
  2. Reduced Immune Function: Chronic loneliness might diminish the immune system’s efficiency, making individuals more susceptible to illnesses.
  3. Higher Blood Pressure: There’s a growing body of evidence suggesting that lonely individuals might have higher blood pressure than their more socially-connected counterparts.
  4. Shortened Life Expectancy: Perhaps the most alarming revelation is that loneliness can shorten one’s lifespan. It’s on par with other well-established risk factors like obesity and smoking.

The Role of Dopamine

The human brain operates on rewards. Dopamine, the “feel good” neurotransmitter, plays a crucial role in this. When we engage in social interactions, our brain rewards us with dopamine. This encourages us to seek more interactions, fostering bonds and relationships.

When isolated, our dopamine levels can plummet. This can initiate a vicious cycle where the lack of dopamine makes us less inclined to seek out interactions, further exacerbating feelings of loneliness. The pleasure we derive from screens, though momentarily boosting dopamine, lacks the depth and warmth of genuine human connection, often leaving us feeling emptier.

The Modern Loneliness Epidemic

A report by Cigna, a global health service company, emphasized the modern loneliness epidemic, especially in the United States. The findings suggest that most Americans are classified as lonely. Younger generations seem to be at higher risk, which is surprising given their tech-savviness and online connectivity.

Factors contributing to this epidemic include increased screen time, decreased face-to-face social interactions, and the cultural shift towards individualism. The structure of modern life, where both family units and communities are less tight-knit than in previous generations, further fuels the crisis.

Tips for Combatting Loneliness

It’s not all doom and gloom, though. Recognizing loneliness as a genuine health concern is the first step in addressing it. Here are some strategies to combat this silent epidemic:

  1. Community Engagement: Engage in community activities. Joining clubs, organizations, or even group fitness classes can foster new connections.
  2. Digital Detox: Allocate specific times in the day to disconnect from digital devices. Use this time to engage in hobbies, read, or take nature walks.
  3. Seek Professional Help: Just as one would consult a doctor for a persistent cough, seeking therapy for chronic loneliness is vital.
  4. Volunteer: Volunteering can provide a dual benefit. It can reduce feelings of isolation while giving individuals a sense of purpose.
  5. Pet Companionship: Animals, especially dogs and cats, can offer comfort and reduce feelings of isolation.
  6. Establish a Routine: Having a daily routine can provide structure, reducing feelings of aimlessness, which can compound loneliness.

Loneliness Kills: Don’t Let It Ruin Your Life

In an age where we can reach out to someone thousands of miles away with a click, it’s paradoxical to witness a surge in loneliness. Recognizing and understanding its profound effects on our physical and mental health is crucial. As with all health risks, prevention and early intervention are key. We must prioritize genuine human connections, value our well-being, and remember that our health encompasses not just our bodies, but our minds and souls as well.

—WTF fun facts

Source: “Loneliness Is as Lethal As Smoking 15 Cigarettes Per Day. Here’s What You Can Do About It” — Inc.

WTF Fun Fact 13485 – People Who Read Live Longer

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In 2016, Yale researcher first published a study that found a connection between longevity and reading – in other words, people who read live longer. It’s a correlation, but there’s no clear causation (that is, there’s no proof that reading is precisely what adds years to your life). Still, it felt validating for those of us who love the written word. And even better, it’s a free activity (if you have access to a library) that’s available to lots of people!

So, Do People Who Read Live Longer?

In an increasingly digitized world, it might be easy to dismiss reading as a leisurely pastime of bygone eras. Yet, plenty of people still do it. So, researchers from Yale University’s School of Public Health decided to expore the benefits of reading to try and understand whether engaging in this mental exercise could have real, tangible effects on longevity.

The study analyzed data from 3,635 individuals aged 50 and above. It divided them into three groups.
1) those who didn’t read books
2) those who read for up to three and a half hours a week,
3) and those who read more than that.

The results? Book readers, regardless of gender, wealth, education, or health, had a 20% reduction in risk of mortality over a 12-year period compared to non-book readers!

Even reading less than 3.5 hours per week benefitted. Reading came with a significant survival advantage over those who didn’t read at all.

Why Does Reading Enhance Longevity?

The exact mechanisms that would explain why people who read live longer are still being explored. But the hypothesis is as fascinating as the result itself.

Reading books, particularly those with complex narratives, demands cognitive engagement and promotes empathetic understanding and emotional intelligence. This intellectual stimulation boosts brain power, much like how physical exercise strengthens the body.

Reading can also provide a healthy form of escapism, reducing stress, and promoting better mental health. This “workout” for the mind might increase resilience against age-related cognitive decline and diseases, leading to an overall longer lifespan.

Not All Reading Is Equal

While all reading is beneficial, the study found that reading books, as opposed to magazines or newspapers, provided a larger survival advantage. This could be because books involve more immersive and cognitive processes, like the use of imagination and critical thinking. They also encourage the reader to make connections between different plot elements spread out over hundreds of pages, creating a greater neural stimulus.

We know what you’re wondering. We’re wondering about it too. What about reading online or on an e-reader? And researchers aren’t sure. But older research found that people who read physical books were more engaged and remembered more plot points. However, we need more research – and those results wouldn’t apply to everyone anyway.

Further research is needed to solidify the connection and understand the exact mechanisms behind why people who read live longer. For instance, how different genres might impact longevity is still an open question. Does a suspense thriller provide the same benefit as a heartfelt romance?

And, of course, as digital reading becomes more popular, future research will need to explore whether reading eBooks – or even listening to audiobooks – provides the same benefits as “traditional reading.”

—WTF fun facts

Source: “People who read live longer than those who don’t, Yale researchers say” — Big Think

WTF Fun Fact 13483 – Lifespan of a Cat Increasing

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The average lifespan of a cat (well, an indoor cat) is around 12 to 15 years, but many cats now can live to be 20. These numbers seem to be trending upward. (Although we have to admit that we haven’t seen this confirmed by researchers anywhere – the evidence appears to be anecdotal).

Factors Influencing the Lifespan of a Cat

Today’s cats appear to be living longer, healthier lives. This is aided by advancements in veterinary medicine and growing awareness about the importance of preventive care.

From lifestyle choices to genetics, every aspect has an influence on how long our fur-buddies can thrive. The following are some of the most significant contributors:

Indoor Versus Outdoor Cats

Like humans, cats’ lifestyles profoundly affect their longevity. It’s no secret that indoor cats tend to live longer than their outdoor counterparts. They are shielded from various risks like diseases, accidents, predators, and harsh weather

The protected environment ensures they enjoy a higher average lifespan, usually about 15-20 years. In stark contrast, outdoor cats face myriad threats that can often cut their lifespan to just 2-5 years.

Preventive Care

Preventive care, like routine check-ups, vaccinations, and flea and tick preventatives, plays a key role in cat longevity. Regular veterinary examinations can help detect potential health problems early, improving the odds of successful treatment.

Early diagnosis and treatment can be life-saving, especially for chronic conditions like kidney disease, common in cats.

Diet and Weight Management

Another significant factor influencing cat lifespan is diet and weight management. Proper nutrition is crucial for the overall well-being of cats. A balanced diet containing all necessary nutrients contributes to longevity.

On the other hand, obesity is a severe issue that can lead to various health problems like diabetes, arthritis, and heart diseases, reducing a cat’s lifespan.

This is starting to sound a lot like people…or any other living thing, really. Don’t play in the road, eat healthy, get exercise, see a doctor when you’re sick…

Genetics and Breeds

Genetics and specific breed characteristics can influence how long a cat lives.

Some breeds are prone to specific health conditions that can affect their lifespan, while others are generally known for their longevity. For instance, Siamese and Maine Coon cats often live well into their teens, with many reaching their early 20s.

The Lifespan of the Oldest Cat

Now, all of this talk of health might have you thinking that it’s the only way to live a healthy life. But let’s think about humans for a moment. Ever read an interview with someone over 100 who insists the secret is bacon or cigarettes or something? Some of this is just random.

The oldest cat on record, Creme Puff, was well-cared for though. She was an astonishing 38 years and 3 days at her death. Her owner also owned the previous oldest living cat! The secret? Some things you really aren’t supposed to give a cat – like caffeine. The diet fed to these cats was largely commercial cat food with some eggs, turkey bacon, broccoli, coffee with creme, and an eye dropper of ref wine every two days!

Don’t try that at home, but maybe do take the owner’s advice to play with your cat as much as possible if you want them to live a long and active life.

—WTF fun facts

Source: “These Are The Signs That Your Cat Will Probably Live a Long Life” — ScienceAlert

WTF Fun Fact 13474 – Once There Were No Mosquitos in Hawaii

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Believe it or not, there were no mosquitoes in Hawaii until the 19th century.

In its early days, Hawaii was a natural utopia, a paradise that existed free of the annoying whine and itchy bites of mosquitoes. Native flora and fauna thrived without the interference of these bloodsuckers. This absence wasn’t by chance, though. Hawaii’s remoteness, surrounded by thousands of miles of open ocean, formed a natural barrier that kept mosquitoes, among other things, away.

The End of No Mosquitos in Hawaii

Everything changed in the early 19th century when mosquitoes finally found their way to the Hawaiian Islands. Brought inadvertently by humans, the first recorded arrival was in 1826 on a trading ship. The invasive species soon adapted to the tropical climate and began to breed in the islands’ plentiful standing water sources, spelling trouble for both the local ecosystem and the human population.

The Mosquito’s Impact on the Hawaiian Ecosystem

Once mosquitoes gained a foothold, the repercussions were significant. Hawaii’s native bird populations suffered drastically. Mosquitoes brought avian malaria and avian pox, diseases to which the indigenous birds had no immunity. This resulted in a significant decrease in bird populations, leading some species to the brink of extinction. The Hawaiian honeycreeper, for example, experienced a substantial decline, with some species entirely wiped out.

Humans also felt the effects of the mosquito invasion. Initially, the islands’ residents were not accustomed to the nuisance of mosquitoes. However, more than just a nuisance, mosquitoes brought diseases like dengue fever and the Zika virus, threatening public health. Moreover, tourism, a significant part of Hawaii’s economy, took a hit as the presence of these pests and the diseases they carried became a deterrent for some tourists.

Current Efforts to Control Mosquito Populations

Today, efforts are underway to control mosquito populations and mitigate their impacts on Hawaii’s ecosystem. Measures such as eliminating standing water, using mosquito repellents, and introducing mosquito predators like dragonflies are part of the strategy. In addition, genetic modification technologies are being explored to reduce the ability of mosquitoes to reproduce or carry diseases.

The late arrival of mosquitoes in Hawaii is a stark reminder of the profound effects human activities can have on isolated ecosystems. Even an event as seemingly minor as a mosquito stowing away on a ship can disrupt a delicate balance, causing ripple effects that last for centuries.

Gone are the days when there were no mosquitos in Hawaii. As the islands grapple with the ongoing challenges presented by mosquitoes, this tale provides valuable lessons about the importance of protecting the world’s unique environments from invasive species.

—WTF fun facts

Source: “The Plan to Restore a Mosquito-Free Hawaii” — Revive & Restore

WTF Fun Fact 13461 – CPR Playlist

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Hopefully you’ll never have to access the CPR playlist on Spotify, but it’s handy to know it’s there when you need it!

The life-saving rhythm of music

Picture this: you’re in an emergency where someone’s life hangs in the balance. The heart has stopped. The breathing’s ceased. Panic sets in. What do you do? For some, the answer may just lie in the beat of their favorite song.

In an innovative move, NewYork-Presbyterian Hospital has turned to music as an unexpected life-saving tool. They’ve curated a Spotify playlist with songs that have the perfect tempo for CPR compressions. The goal? To empower everyone, not just medical professionals, to perform effective CPR.

If you’ve taken a CPR course, you know that timing is everything. The American Heart Association (AHA) recommends a rate of 100 to 120 chest compressions per minute during CPR. Keeping this rhythm, though, can be challenging in the heat of the moment. Enter the NewYork-Presbyterian Hospital’s “Songs to do CPR to” playlist on Spotify.

A playlist with a purpose

This playlist isn’t about entertainment. It’s a practical, life-saving tool. It features 47 popular songs, each one maintaining a tempo of 100 to 120 beats per minute (BPM). This rhythm perfectly mirrors the ideal rate of chest compressions during CPR.

The list brings together classics like “Stayin’ Alive” by the Bee Gees and modern hits such as “Sorry” by Justin Bieber. The idea? By associating the rhythm of these familiar tunes with the pace of chest compressions, anyone can deliver effective CPR.

Hands-only CPR is simple. It involves hard and fast chest compressions in the center of the patient’s chest. This helps maintain blood flow, providing much-needed oxygen to the brain and other organs during cardiac arrest. Matching these compressions to the beat of a familiar song can help maintain the rhythm. But remember, always dial 911 first!

Changing the game with a CPR playlist

The NewYork-Presbyterian Hospital’s playlist isn’t just a clever idea. It’s a life-saver, literally. By combining music with medical knowledge, they’ve given us a unique and memorable tool to use during cardiac emergencies. The best part? It’s not just for the trained professionals. Anyone can use this playlist to guide their CPR compressions, potentially saving a life in the process.

The use of a Spotify playlist for CPR training is a game-changer. By making CPR more accessible and memorable, it shows us how innovation can transform the way we learn life-saving skills. And who knows? The next time a favorite tune plays, you might be tapping your feet to the beat of a life-saving rhythm.

—WTF fun facts

Source: “‘Songs to do CPR to’ playlist could be a lifesaving soundtrack” — Washington Post

WTF Fun Fact 13444 – Sense of Smell Strongest at Night

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Our sense of smell is strongest at night. So if you feel like your pets seem extra smelly, or your bubble bath is a bit too fragrant in the evening hours, you’re not just imagining things. You’re picking up on scents that are somewhat dampened during the day.

Why is smell important?

Smell influences everything from taste perception to memory formation. However, what you may not know is that our ability to detect and discern scents fluctuates throughout the day, peaking during the late hours. This might seem trivial or even surprising, but it is a fascinating aspect of our biology. And it’s linked to our circadian rhythms.

The circadian rhythm is an internal process that regulates our sleep-wake cycle. It repeats roughly every 24 hours and impacts many physiological processes, including hormone release, body temperature, and various neural functions. Interestingly, this includes our olfactory sensitivity – our ability to perceive smells.

During the daytime, our brains process a multitude of sensory inputs. The sights, sounds, and tactile sensations we encounter are processed and analyzed, taking up significant neural resources. Consequently, our sensitivity to smells is somewhat overshadowed by this barrage of information.

Why is our sense of smell strongest at night?

However, the scenario changes at night. As the environmental stimuli decrease and our focus shifts inward, our sensitivity to smells becomes more pronounced. This shift is likely due to changes in body temperature and brain activity that occur during our sleep-wake transition.

The nocturnal enhancement of olfaction has implications beyond being a mere biological curiosity. For one, it directly influences our sleep quality. We are more susceptible to disturbances from unpleasant or potent odors at night. Therefore, the significance of maintaining a fresh and pleasant sleeping environment becomes clear for a good night’s sleep.

Moreover, this increased olfactory sensitivity might have roots in our evolutionary history. Our ancestors needed to be alert to dangers like predators or fires, especially during the night. A heightened sense of smell would have been advantageous in such scenarios, leading to better survival and reproductive success.

On a practical level, this knowledge can be advantageous to various industries, especially those involved in perfume and scent manufacturing. By understanding our olfactory system’s functioning, businesses can tailor their products for maximum impact during the evening hours.

— WTF fun facts

Source: “How Smell Affects Your Sleep” — The Sleep Foundation

WTF Fun Fact 13441 – Dopamine Reward Prediction Error

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The concept of the dopamine reward prediction error is important for understanding the roots of learning, motivation, and even addiction. It’s all about how our brains respond to rewards (and how we get bored with the same reward over time).

What’s the point of dopamine?

Dopamine is a neurotransmitter (or “chemical messenger”) that plays a role in our brains’ reward system. In other words, it’s the star of the show when it comes to feelings of pleasure and satisfaction.

Think about how you feel when you sit down to your favorite meal. Or approach the counter with a long-sought item you saved up money to buy. Happy times! Right?

Well, one particularly interesting (and, frankly, kind of unfair) element of how dopamine functions is that once we already know what a reward will feel like, our brains don’t send out as much dopamine. This is the concept of the dopamine reward prediction error.

What is the dopamine reward prediction error?

Let’s dive a little deeper.

Imagine you’re at a new restaurant for the first time. You order a dish you’ve never tried before. To your pleasant surprise, it turns out to be delicious. Your brain rewards you with a burst of dopamine, creating a sense of pleasure and satisfaction. In essence, your brain is saying, “Good job! Let’s remember this for next time.”

Now, let’s fast-forward to your next visit to the same restaurant. You order the same dish, this time expecting it to be tasty. But here’s the catch – when you take the first bite, your brain’s dopamine release is less intense than the first time. This is because the pleasure derived from the meal was expected. This concept is known as reward prediction error.

Even when you’re eating your favorite meal, it may never taste as marvelous as the first time you had it.

What’s going on in the brain when there’s a dopamine reward prediction error?

Reward prediction error is your brain’s way of comparing the predicted reward (expectation) with the actual outcome. When reality exceeds your expectations, a positive prediction error occurs. And your brain increases its dopamine release.

Conversely, when the actual reward is less than expected (as so often happens in life!), a negative prediction error occurs. Few things are as good as we imagine them to be, and this results in a decrease in dopamine release. (Why did our brains stop playing nice?!)

Why is your brain being a jerk about dopamine?

This dopamine release mechanism seems to play a role in how we adjust our predictions based on outcomes. Technically, it helps us learn from our mistakes and successes. But clearly, it’s not all fun and games. Your brain doesn’t give you a trophy every time you do something good (at least not a big one).

This dopamine-driven learning process can be exploited in harmful ways too. Just think about addiction.

Some drugs generate a significant positive prediction error in our brains. In other words, we take them and (if we survive) we may get a massive release of dopamine that makes us feel great. But this tricks the brain into overvaluing the substance. And this can drive intense cravings and compulsive behavior.

The down side of dopamine

Whether it’s drugs or food or destructive behavior, repeated exposure leads to a decrease in the dopamine response. Unfortunately, this means our bodies require more of the substance to achieve the same effect. That’s addiction.

But here’s the good news – understanding the way our brains respond to reward prediction errors can open up possibilities for new therapeutic approaches. It is helping researchers develop interventions that ‘retrain’ the brain’s reward system to reduce the impact of negative prediction errors and boost our ability to learn from positive experiences.

—WTF fun facts

Source: “Dopamine reward prediction error coding” — Dialogues in Clinical Neuroscience