WTF Fun Fact 13410 – Vibrating Constipation Pill

Who could imagine a future where a vibrating constipation pill could bring on intestinal freedom? Well, here we are.

Jolt your body into action

Constipation. It’s a bummer. Literally. Over 16% of adults worldwide are held captive by its relentless grip, but help could be on the way. Enter the miraculous, yet slightly odd, vibrating pill.

This ground-breaking innovation is brought to you by Vibrant Ltd. They’ve crafted the quirky solution that buzzes its way through your digestive system, essentially shaking things up in there. The aim? To jolt the bowels into action and bring sweet relief to constipation sufferers.

How the vibrating constipation pill works

Packed with miniature mechanics, the vibrating pill buzzes away like a tiny, digestible jackhammer. It’s like a Zumba class for your intestines, really! Vibrations are known to stimulate muscle contraction and that’s precisely what this pill is designed to do – inspire your gut to get moving.

Imagine the possibilities. No more dreaded laxatives with their notoriously unpleasant side effects, replaced instead by a mellow hum lulling your stubborn intestines into action.

The science underpinning this futuristic fix involves the concept of mechanosensation. Our bodies are finely tuned machines, responding to physical forces like pressure and vibration. The idea behind the vibrating pill is to leverage these natural physiological responses to gently coax the bowels into doing their job.

The research

But what do the trials say? According to WebMD (cited below), early results are promising. In a study involving over 200 constipation sufferers, almost half of those who took the vibrating pill saw an improvement in their symptoms. Contrast that with the 12% in the placebo group, and it appears that we have a winner.

Importantly, the pill’s effects seem to persist even after treatment has ended. That’s right – this tiny buzzing wonder may offer long-lasting relief, an exciting prospect for those grappling with chronic constipation.

Still, as with all innovative health technologies, there are hurdles to overcome. The pill must pass rigorous safety and efficacy tests before it gets the green light for general use. Not to mention, the idea of swallowing a vibrating object might need some getting used to for some!

While the vibrating pill may sound like science fiction, it exemplifies the exciting juncture of tech and health. In a world where nanobots and bioelectronics are increasingly becoming part of medical discourse, the vibrating pill represents an ingenious way to tackle an age-old problem.

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Source: “Vibrating Pill Can Help Treat Constipation” — WebMD

WTF Fun Fact 13406 – New Yorkers Bite More Than Sharks

Wait, New Yorkers bite more than sharks? Maybe the ocean isn’t so dangerous after all.

Sure, New York City is a place like no other. It’s a melting pot of cultures and a bustling metropolis teeming with humanity. Yet, lurking in this concrete jungle is an astonishing statistic that puts even the mighty ocean’s apex predator, the shark, to shame. New Yorkers bite people more frequently than sharks do.

The statistics on New Yorkers biting more than sharks

According to the Cleveland Clinic, about 250,000 human bites are reported nationwide each year, nearly 3,500 times more than shark bites. The stat about New Yorkers specifically comes from a 1979 study that found 892 human bites reported in New York City in 1977 – 63 times more than worldwide shark bites that same year. And experts confirm that the stat still stands.

Before the incredulity sets in, let’s chew on the numbers. Each year, according to city health data, New Yorkers register thousands of human bites. The reports aren’t from an emerging trend of cannibalistic tendencies. They spring from the hodgepodge of incidents that result from heated arguments, domestic disputes, barroom brawls, and even lovers’ quarrels.

Who’s afraid of a big, bad shark?

Many people see sharks as menacing dwellers of the deep. They appear in our cultural consciousness as being dangerous predators. Yet they bite fewer than 100 people per annum globally, according to the International Shark Attack File (ISAF). Shark attacks, though undeniably frightening, are statistically minuscule compared to the nipping tendencies of New Yorkers.

Now, this isn’t a crusade to vilify New Yorkers or elevate sharks to sainthood. But it’s a fascinating comparison, one that turns our preconceptions on their heads. It’s a sharp reminder of how our fears and perceptions often dance to the tunes of dramatic storytelling and Hollywood hype, rather than hard facts.

When was the last time you checked beneath your bed for lurking New Yorkers? Likely, never. But ponder the countless hours spent fearing sharks while frolicking at the beach or during a dive. The staggering disparity between the two should, at the very least, get you thinking.

What’s up with New Yorkers?

Stress, alcohol, or just plain old bad temper can lead to teeth being bared and bites being reported. A few bites might even be playful, but city data doesn’t discriminate. New Yorkers are biting at a rate far more ferocious than the most feared shark.

Meanwhile, our oceanic friends glide silently beneath the waves, their reputation tarnished by our overactive imaginations and a few gnashing teeth. We gloss over the fact that sharks play a crucial role in maintaining the health of our oceans, focusing instead on their rather infrequent interactions with humans.

So, let’s flip the script and bite into this juicy factoid. The average New Yorker is more likely to bite someone than to be bitten by a shark. It’s a savory morsel that’s both ludicrous and enlightening, serving as a reminder to keep our fears in perspective and our judgments in check. Sharks might not be the cuddliest creatures in the ocean, but neither are New Yorkers in their concrete jungle.

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Source: “Scared of a shark attack? Here’s what experts want you to know.” — CBS News

WTF Fun Fact 13400 – Brain Processing Speed and Intelligence

Scientists have discovered something interesting about brain processing speed and intelligence. It turns out our decision-making abilities are not necessarily linked to intelligence.

A study by researchers from BIH and Charité – Universitätsmedizin Berlin found that individuals who performed better on intelligence tests were faster at solving simple problems but required more time for difficult tasks compared to those with lower scores.

How is brain processing speed related to intelligence?

In the popular imagination, thinking fast is usually associated with intelligence. There are studies that support this idea, but they might not have been considering a wide enough range of measures.

Personalized brain simulations revealed that brains with reduced synchronization between different regions tended to make hasty decisions. Meanwhile, higher-scoring participants took longer to solve complex tasks and made fewer mistakes. The findings, published in the journal Nature Communications, shed light on the intricate workings of the human brain.

How did they perform the research?

Led by Professor Dr. Petra Ritter, director of the brain simulation section at the Berlin Institute of Health and Charité – Universitätsmedizin Berlin, the researchers employed computer simulations to understand decision-making processes and their variations among individuals. They used digital data from brain examinations, such as magnetic resonance imaging, and mathematical models based on theoretical knowledge of biological processes, to develop “personalized brain models” that mirrored individual participants’ brain activity.

For the study, the researchers collaborated with the Human Connectome Project, which collects data on nerve connections in the human brain. The project provided data from 650 participants who had undergone cognitive tests and obtained IQ scores.

The results of brain processing speed research

The scientists discovered that the brains in both the simulations and real individuals exhibited different behaviors based on their levels of synchronization. Slower brains exhibited higher functional connectivity. This allowed neural circuits in the frontal lobe to delay decisions longer than in less coordinated brains. As a result of the temporal coordination, brains were able to gather more information before reaching a conclusion.

The study also revealed that reduced functional connectivity caused some brains to jump to hasty decisions instead of waiting for upstream brain regions to complete the necessary processing steps. The synchronization of brain regions, forming functional networks, influenced working memory and the ability to hold off on decisions for a longer time. Complex problems required holding information in working memory while searching for alternative solutions, leading to better results.

The research provides valuable insights into the balance between excitation and inhibition in the brain’s decision-making processes and its impact on working memory.

The implications

These findings have implications beyond understanding human intelligence. The improved simulation technology used in the study can potentially aid in personalized treatment planning for patients with neurodegenerative diseases like dementia or Parkinson’s. Computer simulations could help doctors estimate the most suitable interventions, medications, or brain stimulation techniques for individual patients, taking into account the likely efficacy and side effects of each approach.

By uncovering the complexities of brain function and decision-making, this research contributes to our knowledge of the human mind and may open new avenues for personalized medicine and treatment strategies in the future.

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Source: “Intelligent brains take longer to solve difficult problems” — Berlin Institute of Health

WTF Fun Fact 13379 – Benefits of Listening to Birds

In the quest for improved mental health, one often overlooks the simple pleasures of nature. But a recent study published in Scientific Reports revealed the benefits of listening to birds and the profound impact birds can have on our mental health and well-being.

The benefits of listening to birds

Birds offer a unique connection to the natural world, proving to be a source of solace and rejuvenation. Birdsongs possess a remarkable ability to transport us to serene natural environments, even when we reside in bustling urban landscapes.

Research conducted by the Max Planck Institute for Human Development found that listening to birdsongs, even through headphones, can alleviate negative emotions.

Interacting with birds on a regular basis has been strongly linked to better mental health. A study involving 1,300 participants, who documented their well-being multiple times a day using the Urban Mind smartphone app, revealed a significant positive association between seeing or hearing birds and improved mental well-being. Remarkably, these benefits persisted for hours after the encounter.

Even individuals diagnosed with depression displayed positive effects when exposed to birdsong and birdlife in their surroundings. This highlights the importance of preserving and protecting environments that sustain bird populations, as they can provide a natural remedy for mental health challenges.

No need for real birds

In a separate study, participants who listened to diverse birdsongs reported a decrease in depressive symptoms, anxiety, and paranoia. This effect was even observed with just two species of birdsongs, showcasing the potential of these therapeutic sounds.

In contrast, exposure to traffic noise had adverse effects on mental well-being. The study reinforces the significance of nature’s healing aspects and highlights the negative impact of urban environments on our psychological state.

Nature, including birdsong, has a profound effect on our mental well-being. The attention restoration theory suggests that spending time in nature improves concentration and reduces mental fatigue associated with urban stress.

Furthermore, researchers have linked spending time in green spaces to reduced stress, lower blood pressure, and lower cortisol levels. Engaging with nature also promotes physical activity, adding another layer of mental health benefits. Birdwatching, in particular, has been shown to enhance mental health, with individuals who savor the joy of each bird sighting reporting greater benefits.

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Source: “Why birds and their songs are good for our mental health” — Washington Post

WTF Fun Fact 13377 – Tu Youyou and the Nobel Prize

Tu Youyou is a Chinese scientist and pharmaceutical chemist whose groundbreaking work in the discovery of artemisinin revolutionized malaria treatment. Her contributions have had a significant impact on global health, saving countless lives. Interestingly, she sought (and found) the award-winning compound in the corpus of Ancient Chinese Medicine.

According to the Nobel Prize website (cited below): “She is the first mainland Chinese scientist to have received a Nobel Prize in a scientific category, and she did so without a doctorate, a medical degree, or training abroad.”

The training of Tu Youyou

Born in Ningbo, Zhejiang, China, Tu’s interest in medicine may have started after she had to miss two years of school after a bout of tuberculosis.

Tu’s interests eventually landed her at Beijing Medical College. There, she studied pharmacology – a modern science – but with a traditional backbone. At college, she learned how to classify medicinal plants and extract their active ingredients in order to learn more about their chemical structure. She would do this with many of the thousands of plants in the ancient Chinese medical handbooks.

Tu Youyou went to work at the Academy of Traditional Chinese Medicine in 1955, after graduation.

She was first asked by the Chinese government to help find a treatment for malaria during the Vietnam War. Vietnamese soldiers were dying in droves because the disease had become resistant to the standard treatment – chloroquine. But this posed a global health threat. She joined the battle against the disease after Chairman Mao Zedong launched a project called Project 523 in 1967.

Discovering a new malaria treatment

In 1969, Tu became the head of Project 523 and traveled to Hainan Island in southern China. She had to leave her two young children behind for three years to study the disease in its deadly habitat.

After she returned, the scientific work began.

In Beijing, Tu and her team were facing a difficult situation. Over 240,000 compounds had already been tested for their potential use in anti-malarial drugs, but none worked. That’s when they returned to the ancient Chinese medical text.

A reference to sweet wormwood (known as Artemisia annua) would turn out to be the key. She had identified it for its ability to help with “intermittent fevers” – a key symptom of malaria. It had been used in China around 400 AD.

Turning nature into medicine

Through meticulous experimentation, Tu Youyou and her team successfully isolated a compound from Artemisia annua that demonstrated potent anti-malarial properties. She named this compound artemisinin. It was very successful in killing malaria in laboratory tests.

After lab tests came clinical trials, which were also successful. The great thing about artemisinin was that it helped kill malaria while minimizing the development of resistance to the medication. Artemisinin-based combination therapies (ACTs), which combine artemisinin derivatives with other anti-malarial drugs, have since become the gold standard in malaria treatment worldwide.

Tu Youyou’s groundbreaking discoveries earned her numerous accolades and recognition. In 2015, she was awarded the Nobel Prize in Physiology or Medicine, becoming the first Chinese scientist to receive this prestigious honor. Her contributions have had a profound impact on global health, particularly in regions heavily burdened by malaria.

Tu Youyou’s impact on the future

Artemisinin and its derivatives have transformed malaria treatment and played a crucial role in reducing the mortality rate of this deadly disease. Their widespread use has significantly contributed to the decline in malaria-related deaths worldwide. Tu Youyou’s work continues to inspire scientists, researchers, and healthcare professionals in the ongoing fight against malaria.

Despite the remarkable success of artemisinin-based therapies, challenges remain in the battle against malaria. The emergence of drug resistance, particularly in Southeast Asia, underscores the need for ongoing research and innovative approaches to combat this persistent global health issue. Scientists continue to study artemisinin and explore novel drug combinations to stay ahead of the evolving malaria parasite.

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Source: Tu Youyou – The Nobel Prize website

WTF Fun Fact 13355 – Importance of Your Stomach Lining

The mucus in your stomach lining is the unsung hero of your digestive system.

Have you ever wondered why the stomach can digest the things you consume but stops short of digesting itself?

The role of your stomach lining

Mucus may not be something you think about often, but it plays a vital role in our digestive system. And it’s particularly important in the stomach. The mucus lining in our stomach is essential for protecting its delicate tissues from the harsh acidic environment needed to digest food.

Obviously, our stomachs are responsible for breaking down the food we eat. This process involves hydrochloric acid and digestive enzymes, which work together to break down proteins and other food components.

These acids and enzymes are necessary for digestion, but they can also pose a risk to the stomach’s tissues.

And that’s where the stomach lining comes in. If it weren’t for that protective mucus layer, the stomach’s corrosive contents could cause real damage.

The Role of Mucus in Protecting the Stomach

The mucus lining in the stomach acts as a barrier, separating the stomach’s tissues from its acidic environment. It’s made up of water, electrolytes, and glycoproteins, which together form a thick, slippery substance. This mucus coating allows the stomach to carry out its digestive functions without harming its own tissues.

In addition to serving as a physical barrier, the mucus lining also contains substances called bicarbonates, which help neutralize the stomach’s acids. This neutralizing effect further protects the stomach lining from potential damage.

Maintaining a healthy mucus lining

A well-functioning mucus lining is essential for maintaining a healthy stomach. Several factors can contribute to a weakened or damaged mucus lining. These include stress, smoking, excessive alcohol consumption, and certain medications – even common ones like nonsteroidal anti-inflammatory drugs (NSAIDs).

A healthy mucus lining requires a balanced diet and habits that promote overall digestive health. Eating foods rich in fiber, staying well-hydrated, and managing stress can all contribute to a healthy digestive system.

This allows your stomach mucus to create a barrier between the stomach lining and the acidic environment, preventing the stomach from “digesting itself.”

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Source: “Watch: Episode 3: Why doesn’t your stomach digest itself?” — STAT News

WTF Fun Fact 13351 – ChatGPT and Doctors

There are a few interesting relationships between ChatGPT and doctors. In fact, we know doctors are using the generative AI tool to help them diagnose patients. But perhaps more disturbingly, a recent study recently found that ChatGPT was judged as more empathetic than human doctors when responding to patients.

Empathy is an essential aspect of effective patient care, as it allows healthcare providers to connect with their patients on an emotional level and better understand their concerns. That makes it something we can’t simply farm out to machines.

The study of ChatGPT and doctors’ empathy

The study in question assessed the empathetic responses of ChatGPT in comparison to those of human doctors. Researchers used anonymized text-based conversations between patients and their healthcare providers, replacing the doctors’ responses with those generated by ChatGPT. Then, they asked participants to rate the empathy exhibited by each response.

Surprisingly, ChatGPT’s responses were rated as more empathetic than those of human doctors. This finding suggests that AI language models like ChatGPT might have the potential to enhance patient communication and care by providing more empathetic and compassionate responses. It may also suggest that doctors need some better training.

Improving patient communication

There are several reasons why AI might excel in providing empathetic communication in healthcare settings. For starters, AI systems can be programmed to prioritize empathetic language in their responses. This ensures that each patient receives a compassionate and understanding reply, regardless of their sitaution. In contrast, human doctors might sometimes struggle with maintaining empathy due to factors such as stress, time constraints, or even prejudice.

Additionally, AI systems can quickly process and analyze large amounts of data. This allows them to better tailor their responses to each patient’s unique needs and concerns. This personalized communication could help patients feel better understood and supported.

Since AI language models can be updated and improved continuously, they can incorporate the latest research on empathy and communication techniques. As a result, AI-driven communication tools have the potential to evolve and become increasingly empathetic over time.

Limitations of AI in healthcare

Despite the promising results of the study, there are several challenges and limitations to consider when implementing AI in healthcare communication. One major concern is the potential for AI systems to misunderstand or misinterpret patient concerns due to the nuances and complexities of human language. Inaccurate interpretations could lead to inappropriate or ineffective responses, which could negatively impact patient care.

And while AI can generate empathetic responses, it lacks the genuine emotional understanding and human connection that healthcare providers can offer. This limitation could ultimately undermine the therapeutic relationship.

Another challenge is ensuring patient privacy and data security. AI systems require access to sensitive patient information to provide personalized responses. Ensuring that these systems adhere to privacy regulations is crucial for protecting patient trust and confidentiality.

Yet, despite its limitations, it appears AI has the potential to play a valuable role in supporting human healthcare providers and enhancing patient communication. At the very least, AI systems could help manage routine administrative tasks, such as scheduling appointments or answering frequently asked questions, freeing up more time for healthcare providers to focus on direct patient care.

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Source: “ChatGPT Appears More Empathetic Than Human Doctors When Responding To Patients” — IFL Science

WTF Fun Fact 13342 – Lithium in 7-Up

Few people remember the debut of 7-Up in 1929, so it’s no surprise that you might not know its original name. But Bib-Label Lithiated Lemon-Lime Soda was quite a product! And if you read that closely, you might be wondering if they really put lithium in 7-Up. And the answer is yes.

Why was there lithium in 7-Up soda?

As you likely know, lithium is a compound that is used to help people with mental health issues like bipolar disorder and specific kinds of depression. It’s a mood stabilizer.

The soda really did contain the ingredient lithium citrate. And maybe that’s not such a big surprise since there were plenty of medicinal “tonics” on the market in those days that claimed to miraculously cure all kinds of ailments. (Of course, it’s not the only soda with an eye-popping history of ingredients – we’re looking at you, Coca-Cola!)

Interestingly, when 7-Up hit the shelves (right before the great stock market crash), it was competing with HUNDREDS of other lemon-lime sodas. It sold well – and perhaps it’s because people liked more than just the taste! But that may also be because its creator, Charles Leiper Grigg, marketed it as both a healthy and slenderizing tonic.

What’s in a name?

People were attracted to lithiated soda at the time because lithium had a reputation for being healing and restorative. There are naturally lithiated bodies of water that people still visit in order to absorb trace amounts of the compound. Just take a trip to Lithia Springs, Georgia!

Any lithium you’d absorb in water or in the original 7-Uo would be minuscule compared to what psychiatrists prescribe today. It would not have been enough to alter the mind in any significant way. But it could have been enough so that regular drinkers found some benefits in choosing it over other lemon-lime sodas.

In any case, the government saw fit to ban the use of lithium citrate in soft drinks in 1948. Eventually, it just became 7-Up.

Heads up, 7-UP

The big mystery about 7-Up is where the 7 came from – and that we really don’t know. According to a blog by Ada Mcvean from McGill University back in 2017:

“The soda went through a name change to 7 Up Lithiated Lemon Soda, before finally settling on just 7 Up, and a formula with no added lithium. The 7 in the name has no confirmed source, but several theories about its origin. Some soda fans claim that it is derived from the 7 ingredients used in the original recipe, others from the soda having a pH of 7 (which is not true), and others think that the 7 originates from the lithium in the original formula, as this element has an atomic mass of ~7.”

Maybe a historian will dig up Charles Leiper Grigg’s notes someday. But until then, the name will remain a mystery since he took that information to his grave.

 WTF fun facts

Source: “7-Up used to contain lithium” — Gizmodo

WTF Fun Fact 13337 – Light Pollution

Usually, when we think about pollution, we’re worried about smelling it or ingesting it somehow. Simply seeing it isn’t thought of as dangerous. But did you know light itself could be a sort of “pollutant”? Light pollution is a growing problem that is affecting us and our planet in many ways.

What is light pollution, and how does it hurt us?

Light pollution is the use of artificial light that is excessively bright or misdirected. For example, when streetlights or buildings shine light upwards into the sky. Sure, we need a lot of our street lights to keep us safe on roads and sidewalks, but so many lights and lights that are shining so broadly or brightly can really mess up our sleep and our ecosystem.

For starters, excess and misdirected light has serious consequences for nocturnal animals. It can disrupt their migration patterns, feeding habits, and breeding cycles. And as we know, everything on earth is interconnected in some way.

But light pollution also has a direct negative effect on human health. Our exposure to artificial light at night can interfere with our circadian rhythms. So think about how much light you can still see in your room when you shut off your light fixtures. Can you still see lights from streetlamps? Billboard? Store signs? Neighbors’ holiday decorations?

Exposure to light can lead to a range of health problems, including sleep disorders, obesity, and depression. It can also disrupt our hormones.

A waste of energy

Light pollution also requires energy consumption. And as we know, this can produce greenhouse gas emissions. So by reducing light pollution, we can help our ecosystem, ourselves, and reduce the energy consumption that negatively impacts our future.

What can we do to address the problem of light pollution? One solution is “dark-sky friendly” lighting. This means using lighting fixtures that are designed to minimize the pollution. It wouldn’t involve installing all new light fixtures. Rather, it involves the use of shields or hoods that would direct light downwards (which is where we need it to see roads and sidewalks anyway) instead of upwards. Using these fixtures can reduce the amount of excess and misdirected light while keeping us safe.

Most people don’t even know about light pollution and how it affects them. But once they do, they generally take steps to reduce their own contributions to it. (And we bet the neighbors are grateful!)

Reducing your light output might mean turning off unnecessary lights at night, using lower-wattage bulbs, and making sure outdoor lights only shine downwards.

If you’re seeking some darkness in order to see the stars at night, check out the International Dark-Sky Association. It’s a nonprofit organization that works to preserve and protect the night sky, and it has designated more than 100 Dark Sky Places around the world, including parks, cities, and communities that are committed to reducing light pollution and preserving the beauty of the night sky.

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Source: “Light pollution” — National Geographic